448 PHYSIOLOGY AND MORPHOLOGY OF ANIMALS. 



erse that organ, the animal speedily falls into deep 

 coma and dies in a halt hour. Frogs bear well the liga- 

 tion of the liver, because katabolic processes are very 

 slow in these cold-blooded animals; but if a few drops 

 of the blood of a dog dead of ligated liver be injected 

 into a frog's veins it speedily dies if its liver be ligated ; 

 but if its liver be not ligated it is not harmed at all. Evi- 

 dently, therefore, there is formed by katabolism a viru- 

 lently poisonous substance, which is decomposed and ren- 

 dered innocuous in the liver. This is certain. Now, my 

 view is that the manner in which this substance is de- 

 composed is by splitting into glycogen and urea. 



The exact process of change of waste and of albu- 

 minoids generally in katabolism is very obscure and im- 

 perfectly known. Probably it is complex and contains 

 many steps. But the poisonous results of albuminoid 



Animal Life 



Fig. 307. — Diagram illus.r-tlnjj the cenera'.ion of animal heat and 

 animal force, and the products formed in the process. 



descensive change are called in a general way leuco- 

 maines. Now, the propositi-n is that leucomaines are 

 decomposed in the liver in the manner already explained. 

 After this explanation we now repeat the diagram on 

 page 422, with some additions, and are prepared to ex- 

 plain it more fully (Fig. 307). 



This figure, in addition to the general process by 

 which vital force is generated, gives also some details: 

 (1) that amyloids, and probably fats also, are changed 



