PREVENTION, SYMPTOMS AND TREATMENT qc 



muzzle. These later (24-72 hours) rupture and give rise to eros- 

 ions or ulcers. In cows, vesicles arise on the teats and udder and 

 perineum and the milk becomes thick and slimy or colostrum-like, 

 of bad taste and shrinks greatly in quantity. A day or two after 

 the eruption occurs in the mouth, vesicles are seen, accompanied 

 by swelling, redness and heat about the coronets, heels and be- 

 tween the toes of cattle, while in sheep and swine the eruption is 

 often confined entirely to these parts and does not appear in the 

 mouth. There are also salivation, difficult mastication, lameness, 

 mastitis, discharge from the eyes and nose, abortion, and great losses 

 in flesh and milk. 



While recovery is commonly the rule, yet in certain outbreaks, 

 complications — as pharyngitis, bronchitis, foreign-body pneumonia, 

 abortion, bedsores, general skin-eruption, gastro-enteritis, sudden 

 heart or respiratory failure, septic infection of the feet and legs 

 with cellulitis and purulent arthritis, necrosis of bones and loss of 

 hoofs, — lead to considerable mortality. The loss in flesh and milk 

 is said to average $20.00 per cow, and the mortality in light out- 

 breaks is 1 to 3 per cent. ; in severe epizootics, 5 per cent. The dura- 

 tion of the disease is 10 to 20 days in mild attacks ; extending to a 

 year in the malignant type. 



In man, with malaise and fever, appear vesicles on the lips, 

 tongue, pharynx, sometimes on the face, hands (in milkers about the 

 nails and interdigital spaces, with ulceration of these parts), feet, 

 arms and chest. Heat, swelling and burning pain are present in the 

 mouth, with salivation and painful mastication. There may be 

 swelling of the glands about the jaw. The eruption may be gen- 

 eral, and colic, vomiting, diarrhea and dysentery often occur and 

 may prove fatal in infants. 



In human adults the disease is not fatal. 



In making a diagnosis one must eliminate cow-pox and horse 

 pox, ergotism, mycotic stomatitis and foul foot in cattle. In none 

 of these is a similar eruption seen in the mouth nor is general in- 



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