I3 2 DISEASES OF THE DOMESTIC ANIMALS 



The U. S. Agricultural Department recommends the follow- 

 ing to fortify the hog against hog cholera. (We should not be in- 

 clined to place much confidence in its efficacy were it not advised by 

 so good an authority) : Wood charcoal, sulphur, sodium sulphate and 

 black antimony, each i lb., with sodium chloride, bicarbonate and 

 hyposulphite, each 2 lbs. Dose, 1 tablespoon, heaping full, on the 

 feed to each 200 lbs. live weight. 



The use of emetics, cathartics, antiseptics (as calomel, 3i) 

 and antipyretics are of little value as curative agents. Pasteur's 

 vaccine of attenuated bacilli has been used to immunize swine 

 against erysipelas, but causes some deaths (mortality 1 to 4 per 

 cent.), will not immunize all, and the period of immunity lasts for 

 but a year or thereabouts. 



The serum made by the U. S. Bureau of Animal Industry and 

 recently by some states is of the greatest prophylactic value. 



Hog cholera serum is made by hyperimmunizing immune hogs 

 (those who have recovered from the disease) by injections of 

 blood from hogs sick with hog cholera. Then a week or so after 

 this treatment the hyperimmunized hog is repeatedly bled and the 

 serum from this blood, mixed with 5 per cent, of carbolic acid, is 

 employed. It is given subcutaneously by two methods : 1 . The 

 simultaneous method, where 20 c.c. are injected at the same time 

 with a small quantity of blood from an animal sick with hog 

 cholera. This produces a lasting immunity. 2. The same dose of 

 serum is injected alone which gives a transient immunity of sev- 

 eral weeks, unless the animal is soon after exposed to hog cholera, 

 when the immunity becomes persistent, as in the first case. The 

 serum alone then is particularly useful for healthy animals in a 

 herd in which hog cholera already exists. This method of immu- 

 nizing protects 75 to 90 per cent of animals thus treated and may 

 serve to eradicate the disease. Hog cholera immunizing serum is 

 not supplied by the U. S. Government but may be procured by ap- 



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