PREVENTION, SYMPTOMS AND TREATMENT : 6 r 



ism. In the stallion, swelling- of the penis (with vesicles, ulcers and 

 erythema and paraphymosis of the organ), urethral discharge, 

 strangury and swelling of inguinal glands are seen, although only 

 the discharge and strangury may be present. In mares, there is 

 swelling of the vulva, udder and thighs, the animal acts as in " heat," 

 with frequent micturition; the clitoris is swollen, and the vagina 

 congested and the seat of vesicles, papules and ulcers, and is cov- 

 ered with secretion which flows on the neighboring parts. 



The local symptoms disappear and general symptoms occur 

 after weeks or months, when weakness and paraplegia, with great 

 emaciation, ensue. An urticarial eruption, intense pruritus, con- 

 junctivitis, and nasal discharge are often present. The animal falls, 

 and dies in cachexia with decubitus, septicemia or hypostatic pneu- 

 monia after a period of many months or years. The mortality is 

 about 70 per cent. 



A distinct infection, communicated generally by copulation, 

 is seen in many animals — horses, cattle, dogs, sheep, goats and 

 swine — and closely resembles the local condition of the genital or- 

 gans in dourine. It has been called a benign form of the latter, but 

 is due to another germ and is a wholly separate disease. The incu- 

 bation is usually not longer than a week and the disease lasts from 

 a week to a month, and may be distinguished from dourine in lack- 

 ing the development of the secondary symptoms of paralysis, and in 

 affecting other animals than horses. It is characterized by the ap- 

 pearance of a vesicular eruption on the genitals of the male and 

 female and otherwise presenting a condition similar to the local 

 lesions in dourine, and is called Vesicular Exanthema. 



Treatment. — The local treatment of dourine and severe ves- 

 icular exanthema is practically the same. In the early stages, the 

 use of antiseptics and heat is advisable. Irrigation with hot solu- 

 tions of boric acid (saturated), corrosive sublimate (1-2,000) or 

 lysol or creolin (2 per cent.) should be made several times daily. 

 For females, vaginal injections of the lysol solution are best. The 



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