﻿ITS 
  PRODUCTS 
  OF 
  DECOMPOSITION. 
  75 
  

  

  Experiment. 
  Calculation. 
  

  

  Carbon, 
  .... 
  39-69 
  40-27 
  C 
  36 
  216 
  

  

  Hydrogen, 
  .... 
  3*66 
  3*35 
  H 
  lg 
  18 
  

  

  Bromine, 
  . 
  . 
  . 
  . 
  44-68 
  44-72 
  B 
  3 
  240 
  

  

  Nitrogen, 
  .... 
  - 
  2-61 
  N 
  14 
  

  

  Oxygen 
  9-00 
  6 
  48 
  

  

  100-00 
  536 
  

  

  These 
  results 
  agree 
  sufficiently 
  well 
  with 
  the 
  formula 
  C 
  36 
  H 
  18 
  Br 
  3 
  (! 
  pro- 
  

   duced 
  by 
  the 
  substitution 
  of 
  three 
  equivalents 
  of 
  bromine 
  ; 
  and 
  this 
  formula 
  has 
  

   been 
  confirmed 
  by 
  the 
  analysis 
  of 
  its 
  platinum 
  salt, 
  which 
  will 
  be 
  given 
  below. 
  

  

  In 
  such 
  cases 
  as 
  have 
  been 
  hitherto 
  examined, 
  the 
  substitution 
  of 
  three 
  equi- 
  

   valents 
  of 
  bromine 
  in 
  a 
  base, 
  has 
  entirely 
  destroyed 
  its 
  basic 
  properties, 
  but 
  tri- 
  

   bromocodeine 
  is 
  still 
  a 
  base, 
  though 
  an 
  extremely 
  feeble 
  one. 
  Its 
  salts 
  are 
  all 
  

   sparingly 
  soluble 
  in 
  water 
  and 
  amorphous 
  ; 
  and 
  as 
  there 
  is 
  no 
  possibility 
  of 
  ascer- 
  

   taining 
  their 
  purity, 
  I 
  have 
  not 
  pursued 
  their 
  investigation 
  to 
  any 
  extent. 
  

  

  Hydroclilorate 
  of 
  Trior 
  omocodeine. 
  — 
  It 
  is 
  obtained 
  by 
  dissolving 
  the 
  base 
  in 
  

   hot 
  dilute 
  hydrochloric 
  acid, 
  and 
  is 
  deposited 
  on 
  cooling 
  as 
  an 
  amorphous 
  

   powder. 
  

  

  Hydrobromate 
  of 
  Tribr 
  omocodeine. 
  — 
  This 
  is 
  the 
  substance 
  deposited 
  during 
  the 
  

   preparation 
  of 
  tribromocodeine. 
  It 
  is 
  a 
  bright-yellow 
  powder, 
  perfectly 
  amorphous, 
  

   and 
  very 
  sparingly 
  soluble 
  in 
  cold 
  water. 
  On 
  boiling, 
  however, 
  a 
  larger 
  quantity 
  

   is 
  taken 
  up, 
  and 
  deposited 
  unchanged 
  on 
  cooling. 
  

  

  Its 
  analysis 
  gave 
  the 
  following 
  results 
  : 
  — 
  

  

  {7 
  - 
  501 
  grains 
  hydrobromate, 
  dried 
  at 
  212°, 
  gave 
  

   8-868 
  ... 
  of 
  carbonic 
  acid, 
  and 
  

   1-915 
  ••• 
  of 
  water. 
  

  

  {6-840 
  grains 
  hydrobromate, 
  from 
  another 
  preparation, 
  gave 
  

   8-072 
  ... 
  of 
  carbonic 
  acid, 
  and 
  

   1-767 
  ... 
  of 
  water. 
  

  

  3- 
  762 
  grains 
  hydrobromate 
  gave 
  4*865 
  grains 
  bromide 
  of 
  silver. 
  

  

  

  Experiment. 
  

  

  

  Calculation. 
  

  

  

  

  I. 
  

  

  II. 
  

  

  ^ 
  

  

  

  

  Carbon, 
  

  

  32-24 
  

  

  32-18 
  

  

  32-84 
  

  

  C 
  72 
  

  

  432 
  

  

  Hydrogen, 
  . 
  

  

  2-83 
  

  

  2-86 
  

  

  296 
  

  

  H39 
  

  

  39 
  

  

  Bromine, 
  

  

  . 
  , 
  , 
  . 
  

  

  55-03 
  

  

  54-75 
  

  

  Br 
  9 
  

  

  720 
  

  

  Nitrogen, 
  . 
  

  

  . 
  ... 
  

  

  • 
  ■ 
  • 
  

  

  2-12 
  

  

  N 
  2 
  

  

  28 
  

  

  Oxygen, 
  . 
  

  

  . 
  

  

  ... 
  

  

  7-33 
  

  

  *» 
  

  

  96 
  

  

  100-00 
  1315 
  

  

  These 
  results 
  approach 
  most 
  nearly 
  to 
  the 
  formula 
  : 
  — 
  

  

  2 
  (C 
  3G 
  H 
  18 
  Br, 
  N 
  6 
  ) 
  + 
  3 
  H 
  Br. 
  

  

  They 
  present, 
  however, 
  a 
  certain 
  deficiency, 
  both 
  in 
  the 
  carbon 
  and 
  hydrogen, 
  

   and 
  an 
  excess 
  in 
  the 
  bromine 
  ; 
  but 
  no 
  other 
  formula 
  can 
  be 
  found 
  at 
  all 
  approxi- 
  

  

  