﻿252 
  DR 
  ANDERSON 
  ON 
  THE 
  PRODUCTS 
  OF 
  THE 
  

  

  before 
  described* 
  as 
  a 
  product 
  of 
  the 
  action 
  of 
  alkalies 
  upon 
  codeine, 
  under 
  the 
  

   name 
  of 
  Metacetamine, 
  but 
  which 
  I 
  now 
  prefer 
  calling 
  Propylamine, 
  in 
  accord- 
  

   ance 
  with 
  the 
  name 
  now 
  usually 
  applied 
  to 
  the 
  acid 
  with 
  which 
  it 
  corresponds. 
  

   Unfortunately 
  the 
  quantity 
  of 
  propylamine 
  obtained 
  was 
  too 
  small 
  to 
  admit 
  of 
  

   my 
  examining 
  either 
  its 
  compounds 
  or 
  itself 
  with 
  accuracy. 
  It 
  is, 
  however, 
  a 
  

   perfectly 
  limpid 
  and 
  colourless 
  fluid, 
  with 
  a 
  strong 
  pungent 
  odour 
  resembling 
  that 
  

   of 
  petinine, 
  but 
  more 
  ammoniacal. 
  It 
  gives 
  an 
  abundant 
  white 
  cloud 
  when 
  a 
  

   rod 
  dipped 
  in 
  hydrochloric 
  acid 
  is 
  brought 
  near 
  it, 
  and 
  unites 
  with 
  the 
  con- 
  

   centrated 
  acids, 
  with 
  the 
  evolution 
  of 
  much 
  heat. 
  Its 
  hydrochlorate 
  crystallizes 
  

   in 
  large 
  plates 
  closely 
  similar 
  to 
  those 
  of 
  methylamine 
  and 
  petinine. 
  

  

  The 
  discovery 
  of 
  methylamine 
  and 
  propylamine 
  among 
  these 
  products 
  natu- 
  

   rally 
  directed 
  my 
  attention 
  to 
  the 
  probable 
  presence 
  of 
  ethylamine, 
  the 
  interme- 
  

   diate 
  term 
  of 
  the 
  same 
  series 
  ; 
  but 
  as 
  I 
  had 
  not 
  employed 
  any 
  very 
  particular 
  

   precautions 
  in 
  condensing 
  the 
  more 
  volatile 
  products 
  during 
  the 
  successive 
  recti- 
  

   fications 
  to 
  which 
  I 
  had 
  subjected 
  the 
  crude 
  oil, 
  almost 
  the 
  whole 
  of 
  it 
  appears 
  to 
  

   have 
  escaped. 
  By 
  collecting, 
  however, 
  the 
  first 
  few 
  drops 
  passing 
  over 
  in 
  the 
  

   rectification 
  of 
  the 
  portion 
  boiling 
  under 
  150° 
  in 
  hydrochloric 
  acid, 
  and 
  forming 
  a 
  

   platinum 
  salt, 
  I 
  obtained 
  the 
  following 
  result 
  : 
  — 
  

  

  6*930 
  grains 
  of 
  platinochloride 
  gave 
  2-649 
  grains 
  platinum. 
  

  

  This 
  corresponds 
  to 
  38*22 
  per 
  cent. 
  Now 
  the 
  per-centage 
  of 
  platinum 
  in 
  the 
  

   ethylamine 
  salt 
  is 
  39-60, 
  and 
  the 
  result 
  obtained, 
  which 
  is 
  much 
  too 
  high 
  for 
  the 
  

   propylamine 
  salt, 
  shows 
  that 
  I 
  must 
  have 
  had 
  a 
  mixture 
  of 
  the 
  two, 
  which 
  

   might 
  have 
  been 
  separated 
  had 
  I 
  possessed 
  a 
  sufficient 
  quantity 
  of 
  the 
  salt. 
  It 
  will 
  

   readily 
  be 
  understood 
  that 
  a 
  result 
  of 
  this 
  kind 
  could 
  not 
  in 
  general 
  be 
  produced 
  

   as 
  evidence 
  of 
  the 
  existence 
  of 
  ethylamine, 
  but 
  under 
  the 
  particular 
  circumstances 
  

   of 
  the 
  case, 
  the 
  next 
  term 
  of 
  the 
  same 
  series 
  on 
  either 
  side 
  of 
  it 
  having 
  been 
  

   detected, 
  it 
  may 
  be 
  considered 
  as 
  sufficiently 
  conclusive 
  of 
  its 
  presence. 
  

  

  The 
  occurrence 
  of 
  these 
  bases 
  enables 
  us 
  to 
  establish, 
  on 
  satisfactory 
  grounds, 
  

   the 
  constitution 
  of 
  petinine. 
  In 
  the 
  first 
  part 
  of 
  this 
  paper, 
  an 
  analysis 
  of 
  that 
  

   base 
  is 
  given, 
  which 
  agrees 
  in 
  the 
  most 
  perfect 
  manner 
  with 
  the 
  formula 
  C 
  8 
  H 
  10 
  N, 
  

   which 
  was 
  also 
  confirmed 
  by 
  that 
  of 
  its 
  platinum 
  salt. 
  It 
  cannot, 
  however, 
  for 
  a 
  

   moment 
  be 
  doubted 
  that 
  it 
  is 
  homologous 
  with 
  the 
  bases 
  with 
  which 
  I 
  have 
  now 
  

   shewn 
  it 
  to 
  be 
  associated, 
  that 
  its 
  true 
  formula 
  is 
  C 
  8 
  H 
  n 
  N, 
  and 
  that 
  it 
  is 
  really 
  

   butylamine, 
  the 
  corresponding 
  base 
  of 
  the 
  butyric 
  group. 
  The 
  analysis 
  of 
  the 
  

   platinum 
  salt 
  given 
  in 
  my 
  former 
  paper 
  agrees 
  equally 
  well 
  with 
  this 
  formula, 
  and 
  

   though 
  that 
  of 
  the 
  base 
  differs 
  from 
  it 
  to 
  some 
  extent, 
  much 
  less 
  reliance 
  is 
  to 
  be 
  

   placed 
  upon 
  it, 
  as 
  it 
  is 
  scarcely 
  possible, 
  when 
  operating 
  upon 
  so 
  small 
  a 
  scale 
  

   as 
  that 
  upon 
  which 
  I 
  was 
  compelled 
  to 
  work, 
  to 
  subject 
  the 
  bases 
  to 
  a 
  sufficient 
  

   number 
  of 
  distillations 
  to 
  effect 
  their 
  complete 
  separation. 
  

  

  * 
  Edinburgh 
  Philosophical 
  Transactions, 
  vol. 
  xx., 
  p. 
  82. 
  

  

  

  