FINANCIAL DEPARTMENT, ‘CALCUTTA, March 26, 1888. 
~ Apprehensions of the extermination, in their native forests, of the 
-quinine -yielding Cinchona trees having reached an acute stege about 
30 years ago, the Government of India decided to take effectual steps to 
: h i 
pru d 
Cont veas ipie with these efforts on the part ofthe English 
or the Dutch authorities were at work on behalf their 
Malayan Colonies, and by the year 1862, Cinchona cultivation had been 
ent of Cinchona growing in India were the Nilgiris and 
And the excellence of this selection has been proved 
two sorts: (1) quinine yielders, and (2) mixed Alkaloid yielders. Of 
quinine yielders there are two kinds, viz., yelow or Calisaya 
ing ntact Ni and Crown o or officinalis, barks. < Of the mixed 
yielders, there o two kinds, viz., red or succirubra, which 
to para 
y small proportion of quinine, with large proportions of Cinchoni- 
dine and Cinchonine: It had been chiefly used by druggists in the 
ne makers as a source of quinine. This red-bark tree was, 
however, the kind which, in the early days of the cultivation, it was 
found most easy to propagate; and in all pna both public and 
„it Cres preponderated over the other so: 
^ eriment, resin problem that presented itself was “the 
their bark.’ For the private grower, the most lucrative 
sent time, has been to sell the. — bark in 
secure a 
cess, b but to » provide the people e of the nner A ‘at 4 the lowest 
with an efficient uere fe for the most prevalent of all the 
untry. for Government to take was, 
to discover whether it was real a fact that quinine is the only 
hind. unn extracting separately from Cinchona bark, and whether 
Cinchoni idine and Cinchonine might not each be an efficient febrifuge, 
true that a alone had got into ath as a febrifuge, and that 
le ( ef. — hona alkaloids had found a place in the British 
mu ti : agile : 
three alkaloids must undoubtedly enter, had for many years borne 
reputation of ida. comedies for fever. The presumption, 
peared to be that the position claimed for quinine as the 
ly real febrifage Dm ded by Cinchona bark, would prove, on careful _ 
examination, to pn untenable; and that the other vede alkaloids would — 
> found to hav e value as e rpose of 
