141 
investigating this point, commissions of medical officers o all three 
sidencies were formed during the years 1565 to ey Th 
was that Cinchonidine and Cinchonine are both excellent febrifuges, à UA 
former not much less efficient than quinine itself. 
4. Having thus established the value =A Cinchonidine and Cinchonine» | 
to be settled was how bes : 
sts, we 
as Government quinologists on the Nilgiri and Sikkim plantations - 
respectively. Mr. Broughton (the Nilgiri qiinolariat), as the — of 
hi i 
a a misapprehension as as to the “proper dose in which it should be 4 
me prejudice existed against this drug. In 1875-76, however, E 
pounds of it were consumed, and its eonsumption so materially inere 
made and sold in London under the name of Pige i but un 
Cinchona febrifuge had first been manufactured in Indi sim 
preparation existed. It is, therefore, a remedy for which ie world : 
large is indebted to India, Cin chona febri used in India 
as à substitute for quinine, It. 
„been restricted t 
e beginning, and until now, its price has unifo 
6 rupees 8 annas per pound, an dinit a a bes QUE 
contrast to quinine, the pri — vs which. has — neu al 
s been in 
Xo ad at this yoni rate) o ,704 pounds of 
587,6162., ` while this quantity of. febrifuge has. actually 
dian consumer for the sum n of e ‘Rs. 14,47,116, 
