OF THE CALABAR BEAN. 



757 









Experiment LVIIL— 



-continu 



Led. 







Time after 



Mean 



Pressure Oscil- 



No. of 

 Cardiac 



No. of 



Notes of Operations and of 



Time. 



Adminis- 

 tration. 



Pressure. 



lates between 



Contrac- 

 tions. 



Respira- 

 tions. 



Symptoms. 



H. M. 



s. 



M. s. 







Per Min. 



Per Min. 





4 6 



P.M. 



39 10 



7-0 





• ■ • 



24 





4 7 







40 10 



6-9 



60 &78 



116 



23 





4 10 







43 10 



6-8 



5-8 75 



120 



22 



The twitches are now few, faint 

 and occasional. 



4 16 







49 10 



6 8 



5-6 73 



128 



23 





4 17 



30 



50 40 



6-7 



5-8 7-3 





22 



The dog appears almost perfectly 

 well. 



4 19 









69 



55 7-5 



124 





It was deemed advisable to ad- 

 minister a second dose at this 

 stage. 



4 22 







Time after 

 Second Ad- 

 ministra- 

 tion. 











Commenced the injection of four 

 grains of extract, in thirtyminims 

 of distilled water, into the sub- 

 cutaneous tissue of the right 

 flank. 



4 22 



30 









122 



21 



The injection was completed. 



4 23 







30 



6-8 



5-8 7-5 





22 





4 24 







1 30 



6-7 



6-0 75 





23 





4 27 







4 30 



7-0 



58 75 



120 



22 



Strong muscular twitches have re- 

 appeared. 



4 28 







5 30 



6-75 



60 8-0 



116 



21 



Liquid feces passed, and urine 

 " jetted" out in a full and abun- 

 dant stream. 



4 30 







7 30 



7-0 







21 





4 30 



30 



8 



7-35 











4 31 







8 30 



6-9 



6-3 8-3 



120 





Respirations are rather laboured. 



4 33 







10 30 



69 



6-0 80 





22 





4 34 







11 30 



71 



60 80 



118 







4 35 







12 30 



7-2 



6-3 8-0 









4 37 







14 30 



7-4 



6-0 80 





23 





4 38 







15 30 



7-3 



6-5 8-3 



116 



22 





4 42 







19 30 



7-6 



60 83 



120 



24 



Twitches are so strong as to cause 

 frequent slight spasms. 



4 44 







21 30 



7-15 



6-4 7-8 



112 



25 





4 46 



30 



24 



7-2 



6-5 8-5 







Urine and feces discharged 

 copiously. 



4 47 







24 30 



7-5 



65 9-5 





23 





4 48 







25 30 



7-8 



6-0 11-0 



92 



26 





4 49 



30 



27 



7-3 



56 100 



30 







4 50 







27 30 



7-1 











4 50 



15 



27 45 



6-9 











4 50 



30 



28 



67 



5-0 8-5 





23 





4 50 



31 



28 1 



6-2 











4 50 



35 



28 5 



5-9 











4 50 



38 



28 8 



5-8 











4 50 



40 



28 10 



5-4 



4-0 70 



40 







4 51 







28 30 



54 



4-0 4-7 







The twitches continue with con- 

 siderable strength. 



4 51 



30 



29 



6-9 







25 





