DIMETHYL-THETINE AND ITS DERIVATIVES. 579 
ie 
CH 6 cr eico 
| | 
O O 
| | 
C ee 
| 
CH, 
10 CH, 80H, 
The existence of the hemi-hydriodate described further on supports such a 
view. The dehydration requires eight or nine days for completion. 
The loss of water was determined quantitatively, and amounted to 13:1, 
theory requiring 13:0. 
Dimethyl-thetine combines with strong acids such as sulphuric and hydro- 
chloric to form the corresponding sulphate and hydrochlorate; it also com- 
bines with hydriodic acid. Most of its salts are, however, more conveniently 
prepared either from the hydrobromate or sulphate by double decomposition 
with the corresponding silver or barium salts. 
Hudrochlorate of Dimethyl-Thetine.—This salt may be prepared by the 
action of hydrochloric acid on the base, but more conveniently by the action 
of chloride of barium on its sulphate. 
A weighed quantity of the hydrobromate was dissolved in water and treated 
with rather more than the equivalent quantity of sulphate of silver. As soon 
as this ceased to act, the solution was filtered from the bromide of silver, mixed 
with the equivalent quantity of chloride of barium dissolved in water, the mix- 
ture boiled, allowed to settle, and chloride of barium cautiously added till the 
whole of the sulphuric acid was precipitated. The clear solution was then 
filtered off and concentrated in vacuo over sulphuric acid, when, after some 
time, it solidified to a colourless crystalline mass. 
Hydrochlorate of dimethyl-thetine is a colourless crystalline substance, 
having a pleasant sour taste and acid reaction. It is very soluble in water, 
and is deliquescent. In alcohol it is much less soluble, and may in fact be 
precipitated by that liquid from its concentrated aqueous solution. 
The formula— 
CH, 
C,H,SO,Cl = o_$_cH,—coo# 
CH, 
was verified by a chlorine determination— 
Calculated in 100. Obtained. 
Chlorine, : : d 22:7 Zao * 
: * The excess of chlorine was probably due to a small quantity of hydrochloric acid enclosed 
within the crystals, as the specimen analysed was obtained from the base and hydrochloric acid. 
VOL, XXV1II, PART II, 71 
