464 DR T. R. FRASER ON SOME UNDESCRIBED TETANIC SYMPTOMS 



TABLE I. — Summary of Experiments on Frogs — continued. 



Number 



of 



Experiment. 



XV. 



XVI. 

 XVII. 

 XVIII. 



XIX. 



XX. 



XXI. 

 XXII. 



In Grains. 



Weight 

 of Frog. 



432 

 372 

 156 

 508 



455 



404 



300 

 400 



Dose. 



Relation 

 of Dose 



to 

 "Weight 

 of Frog. 



0-4 

 0-35 

 0-15 

 0-5 



0-45 



0-4 



0-3 

 0-4 



XXIII. 



XXIV. 



XXV. 

 XXVI. 



XXVII. 



386 



482 



337 

 234 



465 



0-4 



05 



0-35 

 025 



0-5 



_ i _ 



lU (T 



_ 1 _ 

 lTXo 3 



Region 



of 



Injection. 



i o iTT 



i _ 



Tfo o 



9^ 



1 

 9 6 f 



1 



i 3Tf 



1 

 f3 



Under skin of 

 right flank. 



Do. 



yo 1 ?? Under skin of 

 left flank. 



j-^yz I n *° abdomi- 



nal cavity. 



Do. 



Under skin of 

 left flank. 



Do. 



Do. 



Do 



Effect. 



Under skin of 

 both flanks. 



Under skin of 



left flank. 



Do. 



Do. 



Complete paralysis 1st and 2d days; tetanus 

 3d to 8th days ; stiff spasmodic movements 

 9th day; and perfect recovery 10th day. 

 Complete paralysis 1st and 2d days ; tetanus 

 3d to 6th days ; stiff spasmodic movements 

 7th to 9th days; and recovery 10th day. 

 Incomplete paralysis 1st day; complete par- 

 alysis 2d day ; tetanus 3d day ; and perfect 

 recovery 4th day. 

 Complete paralysis 1st to 4th days ; incomplete 

 paralysis 5th day; tetanus 6th to 8th days; 

 stiff reflex movements 9th to 11th days ; and 

 perfect recovery 12th day. 

 Complete paralysis in 6 hours and at earlier 

 part of 2d day ; incomplete paralysis, 2d to 

 4th days ; tetanus 5th to 22d days ; stiff spas- 

 modic movements 23d day; and death, with 

 commencing rigor, 24th day. 

 Complete paralysis, 1st and 2d days; tetanus 

 3d to 9th days ; stiff spasmodic movements 

 10th and 11th days; and recovery 12th 

 day. 

 Incomplete paralysis 1st day ; slightly exagger- 

 ated reflex movements 2d day ; and death 3d 

 day. 

 Incomplete paralysis 1st day ; complete par- 

 alysis 2d day ; tetanus 3d to 6th days ; irregu- 

 lar tetanus, with twisting of body to left, 7th 

 and 8th days ; stiff spasmodic movements, 

 also with twisting of body to left, 9th to 13th 

 days ; dead, with rigor, 14th day. 

 Complete paralysis 1st and earlier part of 2d 

 day ; exaggerated reflex movements 3d day ; 

 tetanus 4th to 16th days; stiff spasmodic 

 movements 1 7th to 21st day ; stiff movements 

 22d to 24th days ; and perfect recovery 27th 

 day. 

 Incomplete paralysis 1st and 2d days; com- 

 plete paralysis 3d day; exaggerated reflex 

 movements 4th day ; tetanus 5th to 7th days ; 

 stiff spasmodic movements 8th and 9th days ; 

 and death, with rigor, 10th day. 

 Incomplete paralysis 1st to 5th days; and death, 



with commencing rigor, 6th day. 

 Incomplete paralysis 1st to 3d days; tetanus 4th 

 to 12th days; stiff spasmodic movements 13th 

 and 14th days; and perfect recovery 15th 

 day. 

 Incomplete paralysis 1st day; tetanus 2d to 

 4th days ; and death, with commencing rigor, 

 5th day. 



