PRODUCED BY ATKOPIA IN COLD-BLOODED ANIMALS. 



465 



TABLE I. — Summary of Experiments on Erogs — continued. 





In Grains. 



Eelation 







Number 

 of 







of Dose 

 to 



Region 

 of 



Effect. 







Experiment. 



Weight 

 of Frog. 



Dose. 



Weight 

 of Frog. 



Injection. 





XXVIII. 



275 



0-3 



l 



9 17 



Into abdomi- 

 nal cavity. 



Incomplete paralysis 1st day ; complete paraly- 

 sis 2d and 3d days ; incomplete paralysis 

 again on 4th day ; tetanus 5th to 11th days ; 

 stiff spasmodic reflex movements 12th to 14th 

 days; stiff reflex movements 15th day; and 

 unsymmetrical continuous rigidity of the an- 

 terior extremities 16th day, remaining for 

 more than 74 days afterwards. 



XXIX. 



361 



0-4 



1 



9 2" 



Under skin of 

 right flank. 



Incomplete paralysis 1st and 2d days ; complete 

 paralysis 3d day ; tetanus 4th to 6th days ; 

 stiff spasmodic movements 7th and 8th days; 











and perfect recovery 10th clay. 



XXX. 



270 



03 



1 



9 



Into abdomi- 

 nal cavity. 



Incomplete paralysis 1st to 5th days ; and death, 

 with commencing rigor, 6th day. 



XXXI. 



355 



0-4 



1 

 8 8f 



Under skin of 

 right flank. 



Incomplete paralysis 1st day; slightly exagger- 

 ated reflex movements 2d day ; and death 3d 

 day. 



XXXII. 



340 



0-4 



1 



8 5 



Under skin of 

 botb flanks. 



Incomplete paralysis 1st day; exaggerated re- 

 flex movements 2d day ; tetanus 3d and 4th 

 days ; stiff spasmodic movements 5th day ; 

 and perfect recovery 7th day. 



XXXIII. 



251 



0-3 



1 

 8 3 T 



Into abdomi- 

 nal cavity. 



Complete paralysis 1st to 6th days; slightly ex- 

 aggerated reflex movements 7th day ; tetanus 

 8th and 9th days ; stiff reflex movements 10th 

 and 11th days ; complete paralysis 12th day ; 

 and death, with commencing rigor, 13th day. 



XXXIV. 



410 



0-5 



1 



8 "20 



Under skin of 

 both flanks. 



Complete paralysis 1st day ; and death, with 

 rigor, 2d day. 



XXXV. 



403 



05 



1 



?06 



Do. 



Do. do. 



XXXVI. 



638 



0-8 



1 



7 97 



Under skin of 

 left flank. 



Incomplete paralysis 1st day and earlier part of 

 2d ; exaggerated reflex movement latter part 

 of 2d day ; tetanus 3d day ; stiff reflex move- 

 ments 4th day ; and death 5 th day. 



XXXVII. 



396 



0-5 



752" 



Under skin of 

 left thigh. 



Complete paralysis 1st and 2d days ; incom- 

 plete paralysis 3d day ; tetanies 4th to 6th 

 days ; exaggerated reflex movements 7th day ; 

 and death 8th day. 



XXXVIII. 



147 



0-2 



1 

 7 3'S 



Into abdomi- 

 nal cavity. 



Incomplete paralysis 1st day; exaggerated re- 

 flex movements 2d day; tetanus 3d to 10th 

 days ; stiff spasmodic movements 11th to 13th 

 days ; and perfect recovery, 15th day. 



XXXIX. 



214 



0-3 



1 

 Tl3 



Do. 



Complete paralysis, 1st and 2d days ; and death, 

 with commencing rigor, 3d day. 



XL. 



322 



0-5 



1 



Under skin of 

 both flanks. 



Complete paralysis 1st day ; and death, with 

 rigor, 2d day. 



XLI. 



254 



0-4 



1 

 6 3 6 



Into abdomi- 

 nal cavity. 



Complete paralysis 1st to 3d days ; incomplete 

 paralysis 4th and 5th days ; and death, with 

 commencing rigor, 6th day. 



XLII. 



259 



0-5 



1 



3lF 



Under skin of 

 left flank. 



Complete paralysis 1st day; and death, with 

 commencing rigor, 2d day. 



XLIII. 



340 



1- 



3¥5 



Do. 



Do. do. 



VOL. XXV. PART II. 



6D 



