PRODUCED BY ATROPIA IN COLD-BLOODED ANIMALS. 



473 



The observations were now stopped. 



In performing this experiment, care must be taken to avoid injuring important 

 blood-vessels, as any considerable loss of blood would completely vitiate the 

 results. This is at once apparent, if we compare the experiments contained in 

 Table II. with those in Table III. 



TABLE II. — Summary of Experiments in which the Spinal Cord was divided during 

 Atropia-tetanus, without any material loss of blood. ' 



Number 



of 



Experiment. 



In Grains. 



Relation 

 of Dose 



to 

 Weiglit 

 of Frog. 



Effects before the Division 

 of the Cord. 



Time 



of 



Division. 



Effects after the Division 

 of the Cord. 



Weiglit 

 of Frog. 



Dose. 



XLIX. 

 L. 

 LI. 



152 

 294 

 358 



0-15 



03 



0-4 



l 



10 13 



1 



9 8 



1 



8 3~5 



Incomplete paralysis 1st 

 to 3d days; tetanus 4th 

 to 6th days. 



Incomplete paralysis 1st 

 and 2d days ; tetanus 3d 

 and 4th days. 



Complete pai'alysis 1st 

 and 2d days; incom- 

 plete paralysis 3d day; 

 tetanus 4th and 5th 

 days. 



6th day. 

 4th day. 

 5th day. 



Tetanus in both seg- 

 ments 6th to 17th days, 

 and in posterior segment 

 alone 17th to 19th days. 



Tetanus in both seg- 

 ments 4th to 7th days. 

 Frog was killed on 7 th 

 day. 



Tetanus in both seg- 

 ments 5th and Gth days. 

 Frog was killed on 6th 

 day. 



II. — Summary of Experiments in which the Spinal Cord was divided during 

 Atropia-tetanus, with considerable loss of blood. 



Number 



of 



Experiment. 



In Grains. 



Relation 

 of Dose 



to 

 Weiglit 

 of Frog. 



Effects before the Division 

 of the Cord. 



Time 



of 



Division. 



Effects after the Division of 

 the Cord, and oss Lof Blood. 



Weight 

 of Frog. 



Dose. 



LII. 

 LIII. 



LIV. 



272 

 288 



310 



0-25 

 0-3 



0-35 



i 



10 8 8 



l 



J60 



1 



88? 



Incomplete paralysis 1st 

 to 3d days; tetanus 4th 

 to 7th days. 



Complete paralysis 1st 

 and 2d days ; incomplete 

 paralysis 3d day; teta- 

 nus 4th and 5th days. 



Incomplete paralysis 1st 

 to 4th days; tetanus 

 4th to 6th days. 



7th day. 

 5th day. 



6th day. 



Tetanus ceased in 15 

 minutes, and rigor mor- 

 tis was present on 8th 

 day. 



Tetanus of posterior seg- 

 ment ceased in 10 min., 

 but tonic spasm con- 

 tinued in the anterior 

 segment for 24 hours 

 longer. 



Tetanus ceased in both 

 segments in 5 minutes.* 



* In this experiment a large quantity of blood was rapidly lost, as the apex of the heart was 

 excised immediately after the cord had been divided. 



VOL. XXV. PART II. 6 F 



