THE ACTIONS OF PHYSOSTIGMA AND ATROPIA. 



561 





Cardiac 



Restorations, 



Size of Pupils, in 







Contractions, 



per 



fractions of an 



General Symptoms, &c. 





per 10 seconds. 



10 seconds. 



inch. 





In 1 min. 3 sec. 



— 



19 



— 



Infrequent fibrillary twitches at right 

 side. 



4 „ 



32 



14 







6 „ 30 „ 



29 



— 



if ths x if ths 



Movement of lips commenced. 



7 „ 



— 



■ — ■ 



— 



Slight restlessness and some extension 

 of the limbs. 



9 „ 



25 



16 



i£ths x Hths 



The extension of limbs more marked, 

 and some unsteadiness and shaking. 



11 „ 









Excited movements, and often 

 stumbles, while series of tremors 

 occur. 



12 „ 





18 





Head droops, the stiff extension of the 

 limbs has given place to some fiac- 

 cidity and weakness, and the fore 

 limbs often give way. Somewhat 

 soft fseces are passed. 



14 „ 



14 





iiths x iiths 



The respirations are noisy, impeded 

 by mucus, and laboured ; and the 

 animal lies on the abdomen and 

 chest. Saliva escapes freely from 

 the mouth. 



15 „ 



9 





/■g-ths x /„ ths 



The animal is on the side. Infre- 

 quent, laboured, and noisy respira- 

 tions occur, which are accompanied 

 with general struggles. The cardiac 

 impulse is extremely weak. 



At fifteen minutes and ten seconds after the commencement of the injection 

 of sulphate of physostigmia, a solution containing seven-tenths of a grain of 

 sulphate of atropia in ten minims of distilled water was injected under the skin 

 at the back ; and immediately afterwards, the syringe was washed and the few 

 minims of water employed was injected under the skin at the right shoulder. 

 After the commencement of these injections of sulphate of atropia, which were 

 made while the animal appeared to be at the point of death, the following 

 symptoms occurred : — 





Cardiac 



Eespirations, 



Size of Pupils, in 







Contractions, 



per 



fractions of an 



General Symptoms, &c. 





per 10 seconds. 



10 seconds. 



inch. 





In 1 min. 30 sec. 



_ 



7 



5-Vths X /o ths 





2 



50 



18 



5 8 7 ths X /-g-ths 



The cardiac impulse is strong. 



4 „ 



52 



18 



if ths x if ths 



Still on side. The respirations are 

 almost normal in character, and 

 now unaccompanied with moist 

 sounds. Fibrillary muscular twitches 

 very frequent, and occurring over 

 the whole surface. Now and then 

 some spasmodic tremors. 



7 „ . 



59 



— 



— 



The tremors are less frequent, and the 











head is occasionally raised. 



VOL. XXVI. PART II. 



7 G 



