g2e.% REPORTS FROM THE SECTIONS. 
The third stage is one of dementia, mind and body alike suc- 
eumbing to paralysis. There is increasing mental hebetude and 
ual impairment of motive power, defective sphincters, bed 
sores, and then death. 
rapidity, but the average duration of the disease is from eighteen 
months to twoyears. Men die frequently from what may be called 
accidents or secondary illnesses in the course of the disease. In 
women, owing partly to urinary troubles being less marked, partly 
to the more skilful nursing which always obtains in the female 
longer course, and occasionally reaches into the fourth or even 
fifth year, but seldom or never beyond this. 
I do not propose to enter at any length into the pathology of 
general paralysis. All recent investigation tends to show that it 
is primarily a disease of the grey matter of the brain. A chronic 
inflammation of the outer layer of the convolutions, particularly m 
the frontal and parietal regions, and that the pia mater covering 
these is always more or less affected 
The pathological appearances differ, as I need hardly state, 
in different stages of the disease, but in all they point 
aspects of the cerebrum, and in a much less degree over the occl- 
cy } 5 pee | £4} . + which becomes 
d to 
pital portions; th 
into th atter it hasa faded and shallow appearance, 
€ grey matter 1t hasa ands is. The large 
