Experimental data from NYOSL have shown a lack of specificity of anti-tumor 

 activity in various marine invertebrates. A possible growth control role of 

 components of crude and partially purified extracts is suggested. A low 

 molecular weight fraction which showed strong absorbance at 280 nm was 

 obtained. Extracts from 6 species, including Mevcenavia mevcenavia , yielded 

 a fraction which inhibited rate of production of red blood cells in mouse 

 hemopoietic system for inhibition or stimulation of erythrocyte production. 

 Active fractions contained similar and chemically related components; were 

 non-species specific; had wide phylogenetic occurrence (in a ctenophore, 

 sea star, tunicate, lobster, cod, and hard clam); and were capable of acting 

 on growth of normal cells. - J.L.M. 



126 



Bailey, K. 1948. 



Tropomyosin: a new asymmetric protein component of the muscle fibril. 

 Biochem. J. 43: 271-279. 



127 



Bailey, K. 1956. 



Invertebrate tropomyosin. Biochem. J., Proc. 64: 9. 



Adductor muscles of many lamellibranchs contain components which give 

 characteristic X-ray diffraction and electronoptical patterns quite distinct 

 from those of mammalian skeletal muscle. Fibrils responsible for this pat- 

 tern are especially abundant in slow, smooth parts of adductor muscles. 

 The work described here was done on Pinna and oyster adductors. The protein 

 is a tropomyosin. It is even more asymmetric than rabbit myosin. - J.L.M. 



128 



Bailey, Kenneth. 1957. 



Invertebrate tropomyosin. Biochim. Biophys. Acta 24: 612-619. 



Tropomyosin was prepared from Pinna and Octopus muscle. The only mention 

 of Venus mevcenavia was by reference to a paper by Kominz et al . (1957) , 

 abstracted elsewhere in this bibliography and from a personal communication 

 from Dr. K. Laki . - J.L.M. 



129 



Baldwin, John, and Anne M. Opie. 19 78. 



On the role of octopine dehydrogenase in the adductor muscles of bivalve 

 molluscs. Comp. Biochem. Physiol. 61B(1): 85-92. 



High activity of octopine dehydrogenase in adductor muscles of bivalve mol- 

 luscs is associated with a dependence on anaerobic glycolysis during 

 swimming. Studies were done on Pecten alba. Mevcenavia mevcenavia was not 

 studied. - J.L.M. 



130 



Ball, Eric G., and Bettina Meyerhof. 1940. 



On the occurrence of iron-porphyrin compounds and succinic dehydrogenase 

 in marine organisms possessing the copper blood pigment hemocyanin. J. 

 Biol. Chem. 134(2): 483-493. 



Seven species, including Venus mevcenavia , were investigated. Although 

 hemocyanin has been reported in hard clam tissue, its presence is doubtful. 

 Body fluid has a faint bluish color suggestive of hemocyanin, but its 

 presence was not confirmed. Heart and adductor muscles contain iron- 

 porphyrin compounds. Cytochrome spectra have been detected only in heart 

 tissue, and this tissue also contains appreciable amounts of succinic 

 dehydrogenase. Heart muscle also contains myoglobin, and adductor muscles 

 a hemochromogen which resembles myoglobin. Presence of succinic dehydro- 

 genase in adductor muscle is doubtful. - J.L.M. 



36 



