Due to die large number of chemicals available for screening, it was not possible to test the 

 majority of them in duplicate, nor was it considered necessary to do so to fulfill the objectives of the program. 

 Where ambiguous results were observed, tests were repeated until definitive results were obtained. 



METHOD OF REPORTING SCREENING TEST DATA 



An alphabetical list of 3, 939 compounds, with the results obtained in preliminary screening 

 tests of each substance, is presented in Table 1, An additional 407 compounds, identified by code numbers 

 only, are listed with similar test data in Table 2. 



Chemical nomenclature, as employed in Table 1, conforms to the Chemical Abstracts system. 

 In many instances, related chemicals with entirely different names were received from different sources. 

 For this reason, we felt it necessary to adhere to a uniform nomenclature system. The Chemical Abstracts 

 system was adopted because its basis is readily available [See: Subject Index: "Introduction, with key and 

 discussion of the naming of chemical compounds for indexing", Chemical Abstracts, Vol. 59 (1945), 

 pp. 5867-5975]. 



In most cases, consultation of the Fourth Decennial Index or the annual index of a recent year 

 of Chemical Abstracts will suggest the manner in which we have listed a particular class of compounds. 

 Inverted names have been used for substituted compounds. The inverted portion either follows a comma 

 after the parent name or receives a first order of indentation. The substituents are in alphabetical order. 

 Other modifications of the compounds (salts, esters, commercial formulations, etc. ) are either separated 

 from the name by a semicolon or receive a second order of indentation. 



In a few cases, a rational formula could not be constructed from the name given by the 

 supplier. When attempts to resolve this difficulty failed, the name has been entered in the table as received. 

 Materials of unknown or doubtful composition are listed by the name provided by the supplier. In some 

 instances, trivial chemical names have inadvertently found their way into our list (nearly all of these are 

 cross-referenced in the Chemical Abstracts subject indices). 



A number of commercial chemical products were tested in the screening program. Where 

 the chemical identity of these substances was not immediately available, they have been listed directly in 

 Table 1 by trade name. Other products, whose identity was known to us, have been given primary listing 

 by their proper chemical names. A cross-reference index is presented in Table 3 which will aid in locating 

 the latter group of commercial compounds in Table 1. 



For simplicity of tabular presentation, any toxic effects of compounds have been expressed in 

 terms of the elapsed time of exposure required to produce some obvious pathological condition. Thus, the 

 figures given in Tables 1 and 2 indicate the time in hours, fractions of hours, or minutes to cause death or 

 obvious distress. Each time datum represents the average response of all test specimens of a particular species. 



Private concerns, public agencies, and individuals that supplied the compounds tested have each 

 been assigned an identifying number. For tabular convenience, these numerical designations have been 

 utilized in Tables 1 and 2. They may be identified by reference to Table 4 which is a numerical list of 

 sources. An alphabetical list of these sources with their identifying numbers will be found in Table 5. 



