SEA-FISHERIES LABORATORY. 



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preserved in formalin, and sections were made and 

 stained by Mallory's connective tissue method, after 

 previous mordanting in Miiller's fluid. 



The tissue of the tumour was compact and hard, and 

 had all the appearance of a fibroma. But on examining 

 the sections it was seen that it was not a typical 

 fibromatous growth but possessed certain marks of 

 malignancy. Fig. 6, PL III, represents a part of the 



Fig. 5. Cod with Fibro-sarcoma on snout. 



tumour where the fibrous elements were mixed with 

 small round cells. Not all the tumour was so richly 

 cellular as this part, and in the denser parts relatively 

 few cells were present. In other places the cellular 

 elements were, however, much more abundant than in the 

 part represented by fig. 6. In fig. 7, for instance, part 

 of the tumour, consisting almost entirely of irregularly 

 shaped, somewhat stellate cells, is shown; and this may 

 pass into such a tissue as is represented in fig. 8, small 

 round cells, some showing a distinct tendencv to become 

 spindle-shaped. 



Such round-celled tissue, containing relatively little 

 fibrous elements, forms conspicuous nodules in the 



