SEA-FISHERIES LABORATORY. 137 



10. Cutaneous Papilloma from a Halibut (Hippoglossus 

 vulgaris). 



In November, 1911, Mr. F. Stokes, Port Sanitary 

 Inspector at Grimsby, sent me a piece of tissue weighing 

 about two pounds, cut from off the snout of a halibut 

 landed at Grimsby. The fish was about 120 lbs. in 

 weight, and the Inspector was of opinion that it was 

 "well-fed" and in good condition, apart, of course, 

 from the growth on the head. The latter, however, was 

 a very extraordinary one. It was very irregular in 

 shape, so that in the cut-out specimen it was almost 

 impossible to be sure of the relations of its parts to the 

 head of the fish. It was pigmented much in the same 

 manner as the skin of the upper surface of the fish, but 

 was perhaps darker in places. The free surface was 

 everywhere thrown into fungoid, or " cauliflower- 

 shaped " excrescences. In some places these protuber- 

 ances were large, lobulated and botryoidal, presenting 

 in fact a great variety of appearances. In other 

 places the surface of the growth was very minutely 

 papillated, and dead grey white in appearance. It is 

 very difficult to describe the appearance of this growth. 

 It was very hard and dense, presenting in its in- 

 ternal parts all the appearance of a hard fibroid 

 tumour. In the deep the tissue was mainly aggregated 

 in nodular masses, presenting a dead white, sometimes 

 glistening, appearance. The tissue, both directly under- 

 neath the surface of the tumour and in the deeper parts, 

 was very difficult to manipulate when cutting sections. 

 It was extremely hard after embedding in paraffin, and 

 could only be cut wit]) great difficulty. Staining, too, 

 was difficult on account of the formalin fixation, but 

 fairly good results were obtained with Ehrlich'e haema- 



