138 TRANSACTIONS LIVERPOOL BIOLOGICAL SOCIETY. 



over prickle-cells, can hardly be recognised in the region of 

 normal skin. 



The figure shows a flat, wart-like protuberance of the 

 skin, and beneath this protuberance there is a partial dis- 

 integration of the coarse fibrous layer. This disintegration 

 is produced by the down-growth of tissue from the dermis or 

 epidermis, and this tissue penetrating between the connective 

 tissue bundles has led to partial absorption of the latter. 

 The intrusive down-growing tissue consists mainly of fine 

 fibres running in various directions, but between these bundles 

 of fibres are cells arranged sometimes in short cords, and there 

 is also an abundant infiltration of lymphocytes. 



The lesions suggest sarcomatous conditions, but they are 

 not quite like any of those which I have already seen, and 

 melanism is usually absent in the most typical tumours. The 

 condition rather resembles that of an epithelioma, except 

 that there are no traces of squamous epithelium or prickle-cells. 

 The lesions are, however, atypical ones. 



Halibut TOith Benign Tumours in the Body Muscles- 

 Plate IV, figs. 5 and 6. 



On October 30, 1913, Mr. F. Stokes, Port Sanitary 

 Inspector at Grimsby, sent me a large piece of halibut cut 

 from a fish which had come under suspicion. For certain 

 reasons it became necessary to investigate closely the question 

 of the malignancy or otherwise of growths, or tumours, 

 in the flesh of this fish. The halibut was an unripe female, 

 weighing over 2 cwts., and it was apparently well-nourished 

 and in good condition. On the coloured side, behind the 

 body cavity, there were two large lesions; one of these had been 

 removed, the flesh being cut away round and beneath it, the 

 other was intact. The skin had disappeared over a round area 

 about 10 cms. in diameter. The wound so formed was not 

 sunken, and its surface was level with the surrounding tissue, 



