SEA-FISHERIES LABORATORY. 221 



bacilli without result. No tubercular lesions were ever 

 produced in the fish, but these authors showed that acid- 

 fast organisms were to be found in the tissues and 

 organs of these experimental fish, and were viable for 

 a month at least after the feeding experiments had been 

 stopped. 



The relationship between the various types of 

 organisms characterised by the acid-fast staining 

 reaction and isolated from cold-blooded animals, and 

 those organisms which belong to the well-known human, 

 bovine or avian types has been the subject of much study 

 by many authors. The question has not as yet reached a 

 final settlement. 



Two authors alone of the many engaged in this 

 research have succeeded in producing an organism, 

 originally isolated from a cold-blooded animal, which 

 they could accustom to grow at a temperature of 37° — 

 the optimum temperature for organisims isolated from 

 human sources. Friedniann's bacillus isolated from the 

 lung cavity of turtles grew well at 37°, and Aujesky, 

 after much trouble, obtained a strain of the bacillus of 

 fish tuberculosis which would grow at the temperature 

 of the body-heat of a warm-blooded animal, and was 

 even pathogenic for the smaller laboratory animals. 



Dubard, Bataillon and Terre believe that the bacilli 

 of fish tubercle can become human tubercle bacilli. 



Morya, Auche and Hobbs, Lubarsche, Sion and 

 Herr do not believe that fish tubercle bacilli are 

 produced by the passage of human tubercle bacilli 

 through cold-blooded animals. 



Sorgo and Suess have proved to their own satisfaction 

 that human tubercle bacilli can be transmuted into the 

 bacillus of fish tubercle. 



From the point of view of this note, it is to be 



