PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 151 
omposition of Bile before and after Podophyllin. 
The next question to be answered was evidently this, Is the increase in the 
quantity of bile after podophyllin merely due to an increase of water, or are the 
bile-solids also increased? The bile secreted by dog 10, between the second 
Experiment 10. 
Secretion of bile 
per kilogramme of 
dog : per hour. 
| Secretion of bile 
per 15”. 
Bret SIWAS 
NOW PRNNe - 
bo @ 
> 
wow w rp 
wh ee 
boom ee. 
bra ce, 
P 
bo Oo Hm OF Oo ODO 
bh) GH 00 00 ND 
> 
wore 
wdSS| 
= Ww 
Fig. 10.—Secretion of bile before and after podophyllin. 6 ce. bile 
and 6 ce. water injected into duodenum at 6 and 0’. 4 grains 
resina podophylli in the same fluids injected at p. 
hour and a half and the third hour, and that secreted an hour and a quarter 
_after the administration of podophyllin, were analysed with the following 
results (Table IT). 
