152 PROFESSOR RUTHERFORD ON THE 
TABLE II.—Podophyllin. 
Experiment 10. Before. After. 
Water, ; : : : : 90°83 91:07 
Bile acids, pigments, cholesterin, fats, . oO 7°84 
Mucus, 1:00 0°60 
Ash, 0:42 0:49 
100-00 100-00 
Velocity of secretion per half hour, | 46 ce. 9:6 ec, 
| 
It thus appears that, notwithstanding the great velocity of hile-formation, 
the special bile-solids were not diminished; the only noteworthy diminution 
being in the amount of mucus. 
TABLE III.—Podophyltin. 
This remarkable result was confirmed by the 
following analysis of the bile in another case (Table IIL). 
Experiment 10a. Before. After. 
Water, ; : ; ; 94:26 94:28 
Bile-acids, pigments, cholesterin, fats, . 4°66 4:68 
Mucus, 0°73 0°70 
Ash, 0°35 0:34 
100-00 100:00 
Velocity of secretion per half-hour, 1:86 cc. 2-47 cc. 
Results of the Experiments with Podophyllin.—1. Podophyllin, when injected 
into the duodenum of a fasting dog, increases the secretion of bile. 
It is 
inferred that the increased biliary flow in the preceding experiments was due 
to increased secretion, and not merely to expulsion, because the gall-bladder 
had been emptied by compression, and the cystic duct had been clamped: 
moreover, the increased flow was far too prolonged in some of the experiments 
