PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 155 
of purgation. There was a decided increase in the vascularity of the mucous 
membrane in this part of the intestme. The stomach contained a little mucus. 
Its mucous membrane was pale. 
Experiment 11. Experiment 12. | 
| 
Secretion Secretion | 
Secretion | of bile per | Secretion | of bile per | 
of ir in kilogramme jof bile per) kilogramme | 
of dog: per} 15”. of dog: per | 
hour. hour. | 
ee. ce. | 4 
0°85 0°65 | 
0-9 : 0°42 0:5 tt 
0-7 0°348 ce. 0°37 | 
he O°8 | $0-264 ce. | 
0°75 0°3 
1°05 a —— 
1°4 0°35 
1-15 0:97 Fig. 11.—Secretion of bile before and after 60 grains extract ‘of 
1°75 0°697 cc. 0°87 | Socotrine aloes in 12 cc. of water were injected into the duo- 
155 0°85 | denum at a. 
1°55 11 | 
1°4 1:2 
1°3 1°05 ; 
1°45 1°05 0°93 ce. 
1°45 1:35 
1:25 0:8 | 
1°25 abot 
14 al 
1°25 115 
1°25 1:05 
12 1°05 
1°05 Tots 
1:15 0:9 
11 
1°2 
1:0 
0°65 
0'9 
0'9 Fig. 12.—Secretion of bile before and after 60 grains extract of 
he Socotrine aloes in 12 ec. water were injected into the duodenum 
at a. 
Experiment 12. Dog that had fasted eighteen hours. Weight 5 kilo- 
_grammes.—Sixty grains* of extract of Socotrine aloes in 12 cc. of water were 
injected into the duodenum (at a, fig. 12). As in the previous experiment, 
_ the biliary secretion was increased within half an hour, and it became very 
strongly marked. 
| Necropsy.—The aloes had extended half way down ae small intestine. 
_ This portion of the intestine contained about two ounces of viscous fluid; and 
_its mucous membrane, together with that of the stomach, was intensely red. 
* See preceding Note. 
