174 PROFESSOR RUTHERFORD ON THE 
podophyllin, and more reliable when a slight cholagogue action is required for 
a lengthened period.” This statement, however, has been generally neglected,’ 
and the substance appears to be unknown to most persons. 
The substance employed by us was obtained from Messrs Duncan & 
FLockHaArt of Edinburgh. 
Experiment 29. Dog that had fasted seventeen hours. Weight 22°7 kilo- 
grammes (fig. 29).—2 cc. bile and 3 cc. water injected into the duodenum at 0. 
The same with 5 grains of iridin injected at 7. 
Experiment 29. 
Secretion of bile 
per kilogramme of | 
dog: per hour. | 
Secretion of bile 
per 15”. 
o> 
Call aed ell ell lS 
Ee Sw aOS 
or or 
be et 
a 
bd CoE or 
0'227 ce. 
| | 
ORD e 
UK 
ror or or 
boa ce. 
Fig. 29.—Secretion of bile before and after iridin. 2cc. bile and 3 cc. 
water injected into the duodenum at d. 5 grains iridin in the 
same fluid injected at 7. 
HRPDNDNDNDNNNYHENNNH HH EE 
VOD DR OTHE SIS GO ATO SH 
Nercropsy.—Stomach normal, Mucous membrane of upper two-thirds of 
small intestine rather more vascular than usual. This portion of the intestine 
contained 63 cc. of fluid, thus affording evidence of a decided purgative 
effect. 
Experiment 30. Dog that had fasted eighteen hours. Weight 5.4 kilo- 
grammes (fig. 30).—2 ce. bile and 2 cc. water injected into the duodenum at 8. 
The same with 5 grains of iridin injected at 7. 
