176 PROFESSOR RUTHERFORD ON THE 
TABLE XIV. 
| | Secretion of Bile per Kilo- 
gramme of Body-weight _ 
Iridi Patel Woseauitireins | Grains per Kilogramme per bape 
ies: ; 5 of Body2weight: 9; |j:t2 2c) ts | 3 Seu ee 
Before. After. 
Experiment 29, ; 5 with bile, . 0°22 0°22 ce. 0°53 ce. 
7 30, ‘ 5 5 0:92 0:16 ce. 0°63 ce. 
Experiments with Iridin on Man.—In consequence of the striking results of 
the above experiments, we have made many observations with iridin on the 
human subject, and it is certain that we have in this substance a remedy for 
functional hepatic derangement of such value that it will probably in due time 
be universally employed. As yet we have found four grains of iridin a certain 
remedy for biliousness. It may be made into a pill with conserve of roses and 
taken at bedtime. It produces no disagreeable sensations, and on awaking in 
the morning the yellow tongue is clean, and the headache and madaise are gone. 
As iridin, though a powerful hepatic, is not a powerful intestinal stimulant, it 
is well to give in the morning an ordinary mild saline aperient, such as Piillna 
water. Iridin is a more powerful excitant of the liver than euonymin, and a 
more powerful remedy for biliousness,* and is particularly suitable when the 
bilious attack is very pronounced, but we find that when taken two nights in 
succession it is apt to leave a somewhat depressed effect, and therefore it 
probably ought not to be taken more than once a week. Euonymin is there. 
fore to be preferred when repeated stimulation of the liver is required; and 
further, observations which we have made on an elderly gentleman suffering 
from indolent liver and irritable prostate, convince us that iridin is a prostatic 
irritant, and that as euonymin produces no apparent effect on the prostate, it is 
to be preferred as a stimulant of the liver in cases of prostatic irritation. It 
will also be of practical importance to bear in mind that iridin and euonymin 
are both of them diuretics, iridin being the more powerful of the two. 
ACTION OF RESINA LEPTANDR& OR “‘ LEPTANDRIN.” 
“ Leptandria” or “Leptandrin” is a resin prepared from the root of the 
American plant, Leptandra virginica or Veronica virginica, in the same manner 
as euonymin (p. 170). It is a remedy that has been much lauded by the 
* Tt is difficult to say what is the exact cause of biliousness, but it is certain that this condition is 
speedily cured by iridin and euonymin, and that both of these substances powerfully stimulate the 
liver, while they stimulate the intestine to only a moderate extent. 
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