194 PROFESSOR RUTHERFORD ON THE 
Mucous membrane of small intestine exhibited a slightly increased vascu- 
larity. 
Results of Experiments with Rochelle Salt.—It is certainly a hepatic stimulant. 
Experiment 46 shows what a rapid secretion of bile it called forth in a liver that 
was nearly passive before it was given. The effect was by no means so remark- 
able in Experiment 464, where the liver was relatively more active before the 
substance was given. Probably the latter affords a better general indication 
Experiment 46a. | 
Secretion of | Secretion of 
Secretion | bile per kilo-| Secretion | bile per kilo- 
of bile gramme of of bile gramme of 
‘ per 15”. dog: per per 15”. dog: per 
hour. | hour. 
ce. ce. 
ee 075 0°85 | 
0°70 0°90 
0°70 0°95 
0°70 0°85 
pas 0°85 
0 0°75 1:00 
0°80 ; 1:05 0332 ce, 
Fig. 464.—Secretion of bile before and after Rochelle salt. woo an 
3 cc. bile and 55 ce. water heated to 37° C. injected into < O75 0-90 
duodenum at b. The same with 463 grains Rochelle salt 0-70 1°00 
heated to 37° C. injected at 7. 0°70 0-90 
0°80 0°70 
0°90 
than the former of the power of this substance as a hepatic stimulant, and it 
must be remembered that in both cases, especially in the first, considering the 
size of the animals as compared with man, the doses were large; so that, on the 
whole, it may be anticipated that observations on man—now that we specially 
‘direct attention to the matter—will show that this substance stimulates the 
liver, but not powerfully. 
TABLE X XV. 
Secretion of Bile per Kilo- 
gramme of Body-weight 
Rochelle Salt. Total Dose in Grains. pee Dea ee aa | 
Before. After. 
Experiment 46, . 240 46:1 0115 cc. | 0°653 ec, 
Experiment 464, . 463 372 0:236 cc. | 0332 ce. | 
| 
