204 PROFESSOR RUTHERFORD ON THE 
Experiment 52. Dog that had fasted eighteen hours. Weight 17 kilo- 
grammes (fig. 52).—10 grains of 
potassium iodide in 8 cc. of water 
were injected into the duodenum at 
Pp, 20 grains at p’, and 30 grains at 
p’. There was no increase of secre- 
tion, but, on the contrary, a rather 
greater fall than is usually ob- 
served in a normal case. A repe- 
tition of the experiment was there- 
fore necessary. 
Fig. 52.—Secretion of bile before and after potassium iodide. ° 
” At p 10 grains, at p’ 20 grains, and at p” 30 grains in 3 NEcROpSY.—54 ce. of a thick 
Ge, OF watenazs eater toto che auc oaa yellowish mucous fluid found in 
the small intestine, thus affording evidence of a slight purgative action. 
Experiment 52a. Dog that had fasted nineteen hours. Weight 16-9 kilo- 
grammes (fig 52A).—5 grains 
of potassium iodide in 2 ce. of 
water were injected into the 
duodenum at p, 10 grains in 2 
cc. of water at p’, 20 grains in 
5 cc. of water at p”, 30 grains 
in 5 ce. of water at p’”, and 40 
grains in 8 cc. of water at p””. 
The trifling increase of secre- 
tion after the second and fourth 
doses may be discarded, and 
the fall of secretion as the ex- 
Fig. 524.—Secretion of bile before and after potassium iodide. : : 
~ At p 5 grains in 2 cc. of water, at p’ 10 grainsin2ce. of periment advanced might very 
co, of water, andl at p™ 40 grains in 8 ce of wate, nected PTObably have been equally 
age ee cae marked had nothing been given. 
Necropsy.—Small intestine contained 25 cc. of a clear mucous fluid, indi- 
cating a slight purgation ; for, though 22 cc. of water had been injected, much 
of it had doubtless been absorbed. 
Result of Experiments with Potassium Iodide.—This substance does not 
appear to affect the biliary secretion. 
ACTION OF PHYSOSTIGMA. 
Since the well-known researches of Sir Ropert Curistison and Professor 
FRASER, the physiological actions of Calabar bean have been made the subject 
of extensive inquiry; its action on the liver has not, however, hitherto been 
investigated, owing to the want of a reliable method of experiment. As stated 
