PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 215 
of secretion was much higher than in the former experiment (Table XXX), a 
circumstance which was probably largely due to the fact that, while the same 
dose was given in both cases, the subject of Experiment 59 was much smaller 
than that of Experiment 58. The liver of the fifty-ninth dog was, therefore, 
more powerfully affected than that of the fifty-eighth dog. 
Experiment 59. 
Secretion of bile 
per kilogramme of 
dog : per hour. 
Secretion of bile 
per 15”. 
—_—— 0°338 cc. 
2°30 i) 
2°20 j 0°471 ce. 
1°60 
1°95 
Fig. 59.—Secretion of bile before and after phytolaccin. 
2 cc. of bile and 2 cc. of water injected into the 
duodenum at db; 2 grains of phytolaccin with 2 cc. 
of bile and 2 cc. of water injected at p. 
Necropsy.—The small intestine contained 40 cc. of liquid, indicating a mild 
purgative effect. 
Result of Experiments with Phytolaccin.—It is a mild intestinal, but a 
powerful hepatic stimulant, as is shown by Table XXX. 
TABLE XXX. 
Secretion of Bile per Kilo- 
gramme of Body-weight 
< : : Grains per Kilogramme per hour. 
Phytolaccin. Total Dose in Grains. of Bo dy-weight. 
Before. After. 
Experiment 58, . 2 with bile, 0:064 0144 cc. | 0°299 ce. 
”» 59, . 3g 
» 
0:104 0:338 ce. 0°471 cc. 
