PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 217 
dose was given, the bile-secretion had begun to rise, and after the second dose 
the increase was decided. 
Experiment 60. Experiment 61. 
\ Secretion Secretion 
Secretion oa pee Secretion te oe 
of bile per Lp of bile per | P&P “V0” 
15”. g peme 15". shar me 
o ; of dog: 
per hour. per hour. 
GC; ee. 
1:40 ) 07 
1:60 Pei! (0°85 
165 a 230 ec. 0°60 
145 0°35 
—— 0°30 
0°60 0-40 
0°95, 0°30 
: 160 0°35 > 0°09 ce. 
2°15 h —— 
| 1:90 0°17 
| L 175 017 
{—— 0°15 
1:40 010 
0°85 0°30 3 5 7 
| 0 fon 2 3 4 a. 6 7 
855 0°15 Fig. 60.—Secretion of bile before and after hydrastin and 
) 2°45 0386 cc 0°30 sodium salicylate. 2 grains of hydrastin in 2 ce. of 
2°30 j "| 0°35 rectified spirit, 1 cc. of bile, and 2 cc. of water in- 
170 0°55 jected into the duodenum at / and /’; 20 grains of 
2-15 —— sodium salicylate in 10 ce. of water injected into the 
) ote ae lower portion of the intestine at s. 
$ —— 0°80 
ied 0°90 ) | 
1°40 : 
3:95 tis | poser! 
3°45 ’ 1:05 
) 1°10 
0°95 
1:05 
05 
7 
Fig. 61.—Secretion of bile before and after hydrastin. 2 grains of 
hydrastin in 2 ce. of bile, 1 cc. of rectified spirit, and 6 cc. of 
water injected into the duodenum at / and 7’. 
Necrorsy.—Slightly increased redness of duodenal mucous membrane. 
Very slight evidence of purgative action. 
Result of Experiments with Hydrastin.—It is a hepatic stimulant of consider- 
able power, and a feeble intestinal stimulant. The fact shown in Table XXXI.— 
Wor. XXIX. PART I. oui 
