PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 227 
of water at /,; 4 grains in 15 cc. of water at /;; 8 grains in 15 cc. of water at 
Z,; and 10 grains in 15 cc. of water at /;. Thirty grains were given in all. 
The irregularity of secretion rendered the experiment unsatisfactory, and the 
Fig. 67.—Secretion of bile before and after lead acetate and sodium salicylate. 10 grains 
of lead acetate in 20 cc. of water injected into the duodenum at / and /’; 10 grains 
in 10 ce. of water at l’, 7”, and Z’”; 20 grains of sodium salicyate in 10 ce. of water 
injected into the duodenum at s. 
Experiment 67. 
Secretion of Secretion of 
Secretion of bile per kilo- Secretion of bile per kilo- 
bile per 15”. gramme of bile per 15”. gramme of 
dog: per hour. dog: per hour. 
| ce. ce. 
1°8 0°75 
115 0°90 
1:25 U’ — 
1:80 0:95 
1°55 0°95 
1:70 0°95 
1°40 | 0°80 
1°85 | 0°70 
1°55 Yess 
1-20 0°60 
1°60 | 0°80 
1°15 ) 0°70 
12 0°331 ce. : Raya ) 
25 f 0°75 atest 
12 0°65 en 
U 0°55 J 
1:2 | 0°55 
115 | s 
1:10 0°55 : 
0°90 | 1°55 ; 
1-05 210 0°452 ce. 
1°00 2°40 
vv — 
discovery that the acetate of lead used in this and the DreHneus experiments 
was impure, necessitated another experiment. 
Experiment 67. Dog that had fasted eighteen hours. Weight 14°6 kilo- 
