PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 235 
hyoscyamus triturated with 1 cc. of bile and 10 cc. of water were injected into 
the duodenum at /, and the same dose was injected into a lower part of the 
intestine at h’. It is difficult to account for the slight rise of secretion that fol- 
lowed both doses. It may be safely assumed that it was due neither to the 
bile nor to the water. At all events, there was no fall of secretion, notwith- 
standing the administration of sixteen grains of the drug. 
Experiment 73. | 
| 
Secretion 
Secretion of bile per | 
of bile}per kilogramme 
W57, of dog : 
. per hour. 
0-90 
0°85 hoa ee. 
1°25 
1-25 0°288 ce. 
pt 
a) 
X 
a’ — 0°231 ce. 
Fig. 73.—Secretion of bile before and after hyoseyamus and absolute 
alcohol. 8 grains of extract of hyoscyamus in 10 ce. of water 
and 1 ec. of bile injected into the duodenum ath; the same, 
injected into a lower part of the small intestine, at h’ ; 5 cc. 
of absolute alcohol in 20 cc. of water injected into the small 
intestine at @; 8cc. of absolute alcohol in 32 cc. of water 
injected into the small intestine at a’; 20 grains of sodium 
salicylate in 10 cc. of water injected into the duodenum at s. 
cyamus, it was proposed to investigate the action of pure alcohol; accordingly 
5 ec. of absolute alcohol, diluted with 32 cc. of water, were injected into a fresh 
portion of the small intestine, and, as there was no notable effect, 8 cc. of abso- 
lute aleohol in 32 cc. of water were injected into another part of the gut. Not- 
withstanding the administration of 13 cc. of alcohol (219 minims), the bile 
: 
| As the experiment was entirely conclusive regarding the effect of hyos- 
