SOME NEW BASES OF THE LEUCOLINE SERIES. 275 
The filtered solution of the chloride of methyl-tetracoline was cooled in freezing 
mixture, and to it was then added platinum chloride, when the platinum 
salt was precipitated in a fine granular condition, this was washed with ice- 
cold water, then with alcohol and ether, and dried at 100° C. 
Analysis of platinum salt— 
I. 0°187 grms. salt gave— 
0:0465 ,, platinum = 24°87 per cent. platinum. 
II. 0:294 =, salt gave— 
00735 ,, platinum = 25-00 per cent. platinum. 
III. and IV., a mean of the results of two combustions, gave— 
39°75 per cent. carbon. 
These analyses show the body to be the platinum salt of methyl-tetracoline, 
the formula of which, 2C,,H,,NCH,Cl, PtCl,, requires— 
Found 
Calculated ———_—— 
i II. III. 
Carbon, . 39°89 39°75 
Hydrogen, 2 4:09 aE at au 
Platinum, : 25°19 Sat 24:87 25:00 
It is apparent that the chloride of methyl-tetracoline, C,.H,,NCH,Cl, is 
isomeric with the hydrochlorate of pentacoline, C,,H,,NHC1. 
Owing to the very small quantity of material worked upon, we were unable 
to isolate the methyl base, the examination of whose properties would not 
improbably throw very considerable light on the constitution of this series. 
Action of Iodide of Methyl on Pentacoline, C,,H,;N. 
A portion of fraction 305°-310° C., consisting of the base pentacoline, 
C,,H,;N, was heated in a sealed tube with iodide of methyl in the water-bath, 
as in the case of tetracoline. The todide of methyl-pentacoline was obtained 
in olive-green crystals ; these, washed with cold alcohol and dried at 100° C., 
gave on analysis— 
I. 0°26125 grms.crystals dried at 100° C. gave— 
0489 , CO, = 51:24 per cent. carbon. 
Onis4y x) EEOr=. 5°69 i hydrogen. 
II, 01096 ,, gave— 
0:2065 ,, CO, = 51°37 per cent. carbon. 
GOGo, 5; ps0 = 5° hydrogen. 
TTI. 0252 =, gave— 
0481 ,, Agl = 38°80 per cent. iodine. 
IV. 0315 ,, gave— 
02255 ,, AgI = 38°66 per cent. iodine. 
