j * 
1016 The Amerwan Naturalist. [November, 
a later stage of evolution. Responses to stimuli are, however, 
necessarily “fit” or appropriate to the stimulus, and it can only 
be other features in the environment which can make them other- 
wise. And this unfitness cannot continue,—not because its 
possessor is necessarily destroyed, but because new environments 
produce new sensations and new educations. It is therefore in the 
evolution of mind that the doctrine of natural selection breaks 
down completely, even as a directive agent. As an originative 
- method it has no application. 
We have now reached the keystone of the arch of evolution, 
so to speak, and we can retrace our steps over the ground of the 
origin of structure, with which we commenced. The next ques- 
tion which we have to discuss is that of the effect of mental 
conditions on the movements of organisms. 
. 
THREE CASES OF HYPOSPADIAS IN WHICH THE 
SEX WAS UNDETERMINABLE UNTIL PUBERTY. 
BY DRS. L, H. AND W. H. LUCE. 
HESE cases are chiefly interesting from the fact that they all 
occurred in one family; and on account of the slow evolu- 
tion of the organs continuing after birth up to puberty. 
The cases, the subject of this article, consisted of three of six 
children. The parents were of normal development physically, 
but of strong nervous temperaments, there being cases of insanity 
on both sides, —the father on the paternal side, and nieces on the 
maternal side. The father was a sea captain (whaling), intelli- 
gent, of indomitable courage and great energy. The mother was 
also intelligent, and above the average in courage and energy, be- 
longing to a large family of sturdy sea captains celebrated for their 
hardihood. The two did not live happily together; the wife, it 
was said, was frequently the subject of maltreatment at the hands 
of her husband during her pregnancies. There were no cases of 
deformity or deaf mutes in any of the ancestry on either side, 
