132 TRANSACTIONS LIVERPOOL BIOLOGICAL SOCIETY. 



likely that it is caused by a multiplication and separation 

 of young individuals, which break down and leave the 

 host's cells, the intercellular nature of the adults being 

 the only point in which the diffuse infiltration here differs 

 from its occurrence in the Glugece. 



Anyhow, in these, to return to (B), the final result 

 is that the infected area consists of a confused mass of 

 tissue-cells (many broken down), spore-containing cells, 

 and clusters of free spores. In A on the other hand, this 

 process is not evident, and I greatly doubt whether it has 

 been at work. Probably owing to the strong infection, 

 with its attendant effects on the host's metabolism, the 

 parasites do not seem to have attempted to spread further 

 (except, as it were, automatically by growth), but to have 

 concentrated their energies on becoming large spore- 

 forming individuals. The cysts are well-defined, and 

 sharpW limited, and there is no sign of " diffuse 

 Auslaufer." Each is, I consider, the result of growth of 

 a single individual. 



Doflein (I.e.) is of the opinion that the cysts of G. 

 lo'pJiii, which he describes (p. 334 et seq.), result from the 

 fusion of 3-4, and this may well be, for he is evidently 

 dealing with " pseudocysts " and an infiltration con- 

 dition, more or less similar to my specimen B. In A, 

 however, the minute structure shews clearly that each 

 cyst is a single unit. Here the parasites are never, as 

 sometimes in Iiagenmuller's case, in the muscles, but 

 entirely in the areolar tissue of the sub-mucosa. The 

 intestinal epithelium is also free from infection, and 

 though often broken round the much-enlarged internal 

 end of the folds or ruga?, it is still quite evident and 

 normal up the furrows. For a general idea of the size 

 and arrangement of the cysts, the reader is referred to 

 Johnstone's fig. 2, PI. D. 



