300 



DR A. J. WHITING ON THE 



No. of 



Hemorrhage, percentage of body 



Haemoglobin fell to 



Result on Spleen as regards 



Experiment. 



weight. Days' interval. 



Nucleated Red Cells. 



X. 



2-3 per cent. 



Seven days. 

 3 per cent. 

 Three days. 

 3 per cent. 

 Two days. 

 3 per cent. 









Three days. 



39 per cent. 







Three days. 





Great numbers. 



They describe the naked eye appearance of the spleen after copious haemorrhage as 

 characteristic ; it is rose-coloured and much swollen. While they examined the splenic 

 pulp microscopically in the fresh condition, both with and without indifferent fluids, 

 they apparently attended to the nucleated red cells alone, and they do not record any 

 examination of sections of the spleen. 



Dr Eobert Muir # produced anaemia in three dogs, and observed especially the 

 accompanying changes in the red bone-marrow. He was good enough to give me the 

 spleens of these dogs for microscopic examination, and the following is a summary of his 

 observations that bear especially on that examination. 



No. of 

 Experiment. 



Haemorrhage, per- 

 centage of body weight. 

 Days' interval. 



Result on Blood. 



Result on Spleen ; 



Nucleated Red 



Corpuscles. 



1. No. of Red 

 Corpuscles. 



2. Nucleated Red Corpuscles. 



I. and III. 



2 per cent. 



Seventeen days. 



2*5 per cent. 



Six days. 

 2-3 per cent. 



Three days. 

 2*3 per cent. 



Eight days. 



On 3rd day. 



On 8th day. 



(7,460,000) 



2,884,000 

 4,280,000 



None. 

 Present during last 1 2 days. 



A few. 



II. 



2-8 per cent. 



Four days. 



2*5 per cent. 



Nine days. 

 On 3rd day. 

 On 9th day. 



(6,098,000) 



2,451,000 

 3,311,000 



Present during last 11 days. 



A few. 



IV. 



2*85 per cent. 



Four days. 

 2-5 per cent. 



Nine days. 

 On 2nd day. 

 On 9th day. 



(5,830,000) 



2,555,000 

 3,379,000 



Present during last 9 days. 



Present. 



* Mum (47), p. 491. 



