340 DR THOMAS R. FRASER ON STROPHANTHUS HISPLDUS. 



the cardiac impacts 36, per 10 sec, and the right pupil measured i^x j^ths of an inch. 

 The rabbit was sitting quietly in a normal posture. In 14 min., the respirations were 

 20 per 10 sec, and irregular. In 27 min., the respirations were 26, and the cardiac impacts 

 33, per 10 sec. In 35 min., the respirations were 15, and the cardiac impacts 34, per 10 

 sec In 52 min., nearly constant " nodding " movements of the head were occurring. 

 In 58 min., the head was resting on its side upon the table, and the thoracic extremities 

 had yielded so that the thorax was on the table, while the back remained well arched. 

 The rabbit usually remained in this posture, but every now and then a series of "nodding" 

 movements of the head occurred, especially when any voluntary movement was attempted. 

 In 1 hour, the respirations were 17, and the cardiac impacts 35, per 10 sec, and the 

 pupils measured 50 x ^ths of an inch. In 1 hour 2 min., the respirations were 14, and 

 the cardiac impacts 36, per 10 sec; and the respiratory movements had become abrupt 

 during expiration, and were mainly abdominal. Faint tremors were occurring in the 

 head and shoulders. In 1 hour 7 min., the respirations were 12, and the cardiac impacts 

 23, per 10 sec, and the movements of respiration were shallow and abdominal, and with 

 abruptness of both inspiration and expiration. In 1 hour 10 min., the respirations were 

 9, and the cardiac impacts 6, per 10 sec, and the rabbit was now lying flaccid on the side. 

 In 1 hour 15 min., the cardiac impacts were 8 per 10 sees., but only irregular and 

 infrequent respiratory movements occurred about 3 times per 10 sec The cornea and 

 conjunctiva were sensitive, but the right pupil measured -^ x soths of an inch. In 1 

 hour 17 min., the respirations were merely faint and infrequent gasps ; the pupils became 

 dilated to 1% x sjjths of an inch, and no cardiac impacts could be felt, although on stetho- 

 scopic examination a few faint heart sounds were heard at irregular intervals. 



Two min. after death, the heart was exposed, and it was found to be contracting 

 irregularly at the rate of 7 per 10 sec. The pupils had now contracted to 5% x /oths of 

 an inch. Twelve min. after death, the heart was still contracting, but only at long and 

 irregular intervals ; and all spontaneous cardiac movements ceased 15 min. after death. 



Experiment VIII* — In a rabbit, weighing 4 lbs. 2 oz., it was found that the respira- 

 tions occurred 42 times and the cardiac impacts 49 times in 10 sec, and that the pupils 

 measured £§ x Mths of an inch, immediately before 0"05 grain of extract was injected 

 under the skin at the left flank. In 3 min., the respirations were 43 per 10 sec, and the 

 animal was restless. In 7 min., the cardiac impacts were 41 per 10 sec, and the 

 pupils ^oxAoths of an inch. In 8 min., the respirations were 47, and the cardiac- 

 impacts 36, per 10 sec. In 9 min., the respirations were 39, and the cardiac impacts 39, 

 per 10 sec. Grinding movements of the teeth occurred. In 12 min., respiration was 

 laboured, and a sharp sound (like a " smack ") occurred with them. In 13 min., the 

 cardiac impacts were 36 per 10 sec, and decidedly reduced in strength. In 14 min., the 

 respirations were 9 per 10 sec, and the pupils £$x$$tli8 of an inch. In 16 min., tin; 

 respirations were 10 per 10 sec, and the cardiac impacts could not accurately be counted, 

 but they appeared to be at the rate of 38 per 10 sec. In 24 min., the respirations were 



* Published in 1872, Journal of Anatomy and Physiology, vol. vii. p. 147. 



