DR THOMAS R. FRASER ON STROPHANTHUS HISPIDTJS. 



371 







Min. Stimulus re- 









Min. Stimulus re- 









quired to cause Con- 









quired to cause Con- 







Conditions of 



traction of Muscle 







Conditions of 



traction of Muscle 





Time. 



Experiment and 



when applied to 



Notes. 



Time. 



Experiment and 



when applied to 



Notes. 





Notes. 









Notes. 







Nerve. 



Muscle. 



Nerve. 



Muscle. 







Mm. of 



Secondary 



Coil. 



Mm. of 



Secondary 



Coil. 









Mm. of 



Secondary 



Coil. 



Mm. of 



Secondary 



Coil. 







Muscle also 







Fi brillary twitches 





Both nerve and 











placedin above 







are less frequent 





muscle placed in 











strophanthin 







and strong. 





normal saline. 











solution 



















5.16 





230 

















5.20 





220 





Fibrillary twitches 

 are only infre- 

 quent. 













5.35 







80 



Very rarely feeble 

 fibrillary 

 twitches. 













5.46 





70 





Do. Very faint 

 contraction on 

 stimulation of 

 nerve. 













5.55 





50 





Do. 



5.58 





210 





No spontaneous 



6.2 



No contraction 

 when nerve 

 stimulated, 

 even with the 

 secondary at . 







80 



Do. 











fibrillary twitches. 



6.5 



Do. 







80 



Do. 



6.10 





210 





Do. 



When, therefore, a motor nerve-trunk was placed in solution of Strophanthus in 

 saline, its conductivity was not lessened in 1 hour and 3 min. ; but when the muscle 

 containing peripheral endings of the motor nerve was placed in the same solution of 

 Strophanthus, the nerve altogether failed to excite contraction of the muscle in 1 hour 

 and 53 min., although the muscle supplied by the now paralysed nerve still responded to 

 direct stimulation. 



Eesults of a similar description were obtained in the next experiment. 



[Experiment LI. 



