372 



DR THOMAS R. FRASER ON STROPHANTHUS HISPIDUS. 



Experiment LI. — Nerve-Muscle Preparations of both Pelvic Extremities of a Frog, 

 prepared in the same way as in Experiment L. 



A. B. 







Min. Stimulus re- 









Min. Stimulus re- 









quired to cause Con- 









quired to cause Con- 







Conditions of 



traction of Muscle 







Conditions of 



traction of Muscle 





Time. 



Experiment and 

 Notes. 



when applied to 



Notes. 



Time. 



Experiment and 

 Notes. 



when applied to 



Notes. 



Nerve. 



Muscle. 



Nerve. 



Muscle. 







Mm. of 



Mm. of 









Mm. of 



Mm. of 









Secondary 



Secondary 









Secondary 



Secondary 









Coil. 



Coil. 









Coil. 



Coil. 





2.5 



Both nerve and 

 muscle placed 

 in 075 per 

 cent, saline. 









2.5 



Both nerve and 

 muscle placed 

 in 075 per 

 cent, saline. 









2.10 





190 







2.12 





190 







2.15 



Nerve placed 

 in solution of 

 strophanthin 

 (1 :1000). 

 Muscle left in 

 normal saline. 









2.14 



2.20 



2.25 

 2.35 



Muscle placed 

 in solution of 

 strophanthin 



(1 : 1000). 

 Nerve left in 

 normal saline. 



170 



170 

 170 





No spontaneous 

 fibrillary twitches. 



Do. 



Do. 



2.40 





210 







2.45 

 2.55 

 3.5 





170 

 170 

 180 





Do. 

 Do. 

 Rarely spon- 



3.7 





210 





No spontaneous 

 fibrillary twitches. 



3.10 





210 





taneous fibrillary 

 twitches 

 Do. 



3.15 





210 





Do. 



3.25 

 3.30 

 3.35 





200 



200 

 180 





Nearly continuous 

 fibrillary twitches. 

 Do., and fre- 

 quently strong. 

 After contracting, 

 the muscle re- 

 mains contracted 

 for au unusually 



3.42 





200 





Do. 



3.45 



3.50 

 4.0 





180 



190 

 190 





long period. 



Nearly continu- 

 ous moderately 

 strong fibrillary 

 twitches. 



Nearly continuous 

 but feeble fibril- 

 lary twitches. 



Rarely feeble 



4.15 





210 





Do. 



4.20 



4.25 

 4.35 



No contraction 

 when nerve 

 stimulated, 

 even with the 

 secondary at . 







90 

 90 



fibrillary twitches. 



Feeble fibrillary 

 twitches very 

 rarely. 



Fibrillary twitches 

 have ceased. 



Onlyfaintcontrac- 



(.:;>; 





170 





Do. 



5.5 

 5.35 







80 

 60 



tion is produced 

 by the direct 

 stimulation. 



Do. 60, however, 

 produced moder- 

 ately strong con- 

 traction. 



Only faint con- 



5.38 





170 





Do. 











traction. 



On the following day, 23 hours after the last 



note, the strongest 



Ont 



le following day, 23 hours after the lasl 



note, the strongest 



galvanic shocks when applied to the nei 



ve did not produce 



g a 



vanic shocks produced merely a fain 



; depression of the 



any elfect, but when applied to the muse 



le produced a faint 



mi 



tsele between the electrodes, but on 



y if the electrodes 



depression of it. A cut section of the n 



tuscle was alkaline 



wc 



re not far apart. A cut section of tl 



e muscle was alka- 



in reaction. 





lir 



e in reaction. 





