406 DR THOMAS R. FRASER ON STROPHANTHUS HISPIDUS. 



12.1. Eeart's contractions 10 per 30 sec. Systole good ; the diastolic movement seems now of same 



length as the systolic ; no pouching of ventricle. 

 12.5. Heart's contractions 8 per 30 sec. Ventricular diastole less complete; a small area at apex 



remains continuously pale ; auricles are large and dark. 

 12.7. Heart's contractions 10 per 30 sec. A larger area at apex remains continuously pale; ventricle 



smaller. 



12.9. Only a small area at right hase of ventricle now dilates and darkens during diastole; ventricle small. 



12.10. Ventricle motionless, small, and pale ; auricles contract 8 per 30 sec. 

 12.12. Do. do. 



12.15, Heart's contractions 6 per 30 sec, regular and rhythmical; but while the auricles expand and 



contract well, the ventricular diastole consists merely of an extremely faint darkening of the 

 ventricle, immediately followed by a return to a condition of paleness. 



12.16. Ventricle again entirely motionless in extreme systole; auricles contract 6 per 30 sec, and they 



are large and dark during diastole, especially the left auricle. 

 12.21. Ventricle remains motionless in extreme systole; auricular contractions irregular, 4 and 6 per 



30 sec. 

 12.24. Auricular contractions 6 per 30 sec, feeble. 



12.26. Auricular contractions irregular in time and strength and usually extremely feeble ; ventricle still 



motionless in extreme systole. 

 12.27 to 12.34. Auricular contractions 1 per 30 sec. 



12.37. No contractions of auricles ; the left auricle is moderately large ; the right is small. 

 12.38 to 1.28. Do. 



1.30. Do. Irritation of ventricle does not produce any movement ; irritation of auricle produces a very 



faint contraction, which is slow and almost restricted to the part of the auricle that was 

 irritated. Irritation of skin causes active general reflex movements. 



1.31. Excised the heart : the ventricle contains a minute quantity of blood ; the auricles contain much 



blood. 

 1.35. Sections of the walls of the ventricle have an acid reaction. 



Experiment CIX. — Weight of frog, 670 grains. 0'006 grain of sulphate of atropine 

 was applied to the heart's surface before O'OOl grain of strophanthin. 



10.15. Brain destroyed. 



10.21. Heart exposed, and pericardium removed from its anterior surface. 



10.24 to 10.25. Heart's contractions 17 per 30 sec. Diastole abrupt; systole relatively long, but when 

 complete the ventricle is still dark. 



10.27. Applied to surface of heart - 003 grain of sulphate of atropine in solution. 

 10.30. Heart's contractions 17 per 30 sec. 



10.33. Heart's contractions 18 per 30 sec. 



10.34 to 10.41. Heart's contractions 19 per 30 sec. Ventricle does not become pale at end of systole. 



10.42. Applied to surface of heart - 003 grain of sulphate of atropine in solution. 



10.49 to 10.52. Heart's contractions 19 per 30 sec. 



10.53 to 10.54. Applied to surface of heart 2 minims of solution of 0-05 grain of strophanthin in 100 



minims 06 per cent, saline ( = O'OOl grain). 

 10.58 to 11.8. Heart's contractions 18 per 30 sec. 



11.9. Heart's contractions 18 per 30 sec. Ventricle, and especially its apex, becomes paler in systole. 

 11.12. Heart's contractions 17 per 30 sec. Ventricular systole is longer, and during it ventricle becomes 



smaller and paler than before strophanthin had been applied. 

 11.13 to 11.25. Heart's contractions 16 per 30 sec. Do. 



11.28. Do. Ventricle remains dark in systole; diastole is very complete. 

 11.31 Do. Both systole and diastole very complete. 



11.34 to 11.40. Do. do. 



