DR THOMAS E. ERASER ON STROPHANTHUS HISPIDTTS. 407 



11.42. Heart's contractions 14 per 30 sec. Ventricular systole prolonged; diastole brief and abrupt. 



11.44 to 11.46. Do. do. 



11.47. Heart's contractions 10 per 30 sec. Often a slight pause at the end of completed diastole. 



11.52. Heart's contractions 9 per 30 sec. Systole greatly prolonged ; diastole abrupt. 



11.54. Do. Ventricular systole strong and prolonged, and frequently having a peristaltic character. 



11.56 to 12.1. Heart's contractions 10 per 30 sec. 



12.4. Heart's contractions 11 per 30 sec. Ventricular diastole abrupt ; systole prolonged, and area near 



apex remains continuously pale. Tbe pauses are in systole, and the ventricle dilates but little 



during diastole, which consists of an abrupt and Dot great expansion immediately following the 



contraction of the auricles. 

 12.7. Heart's contractions 9 per 30 sec. Auricles large; ventricle, even when blood forced in by 



auricles, scarcely one-half the original size, and nearly the whole of the posterior half is 



continuously pale. 

 12.9 to 12.18. Do. Ventricle latterly very small, only a narrow strip, behind and extending from 



base to near apex, darkens when the auricles contract, and the pauses are in ventricular systole. 



Some general struggles. 



12.22. Auricles now contract feebly, and cause merely a faint and brief redness of the small ventricle. 



General struggles. 



12.23. Auricles contract 11 times per 30 sec. No ventricular movement, and ventricle continuously pale. 

 12.27. Auricles contract 10 times per 30 sec, the contractions being at times strong and at other times 



very feeble ; frequent general struggles. 

 12.36. Auricles contract 7 times per 30 sec. Ventricle motionless, pale, and small. 

 2.20. Excised tbe altogether motionless heart: ventricular cavity empty; sections of the walls of the 

 ventricle tested with blue litmus-paper gave a distinctly acid reaction. 



Experiment CX. — Weight of frog, 860 grains. Two applications, each of 0*003 grain 

 of sulphate of atropine, before application of 0'00075 grain of strophanthin. 



12.24. Destroyed the brain. 



12.29. Exposed the heart, and removed pericardium. 



12.32. Heart's contractions 17 per 30 sec. Diastole of ventricle abrupt, systole longer, but ventricle 



remains dark throughout systole. 

 12.35 to 12.40. Do. do. 



12.41. Applied to surface of heart - 003 grain of sulphate of atropine in solution. 



12.45 to 12.50. Heart's contractions 20 per 30 sec. During systole, the ventricle becomes only slightly pale. 

 12.51 to 12.55. Heart's contractions 21 per 30 sec. Do. 



12.56. Again applied to surface of heart - 003 grain of sulphate of atropine in solution. 

 12.59 to 1.3. Heart's contractions 21 per 30 sec. 

 1.8 and 1.11. Heart's contractions 19 per 30 sec. 

 1.13. Applied to surface of heart 1 minim of solution of - 05 grain of strophanthin in 100 minims 



( = 0-0005 grain). 

 1.15 to 1.26. Heart's contractions 19 per 30 sec. Diastole still abrupt; systole more complete than formerly. 

 1.30. Heart's contractions 17 per 30 sec. 

 1.32. Heart's contractions 16 per 30 sec. Faint interruption before extreme diastole of ventricle; both 



systole and diastole complete. 

 1.35 to 1.49. Heart's contractions 14 per 30 sec. Do. 



1.54. Heart's contractions 13 per 30 sec. Do. 



Observations interrupted until 



2.40. Ventricle and auricles very large and dark and motionless. 

 2.42. Strong general struggles, when contractions of heart recommenced. 



2.47 to 3.23. Heart's contractions irregular, 7 per 30 sec. Often two contractions follow each other 

 quickly, and then a pause occurs in extreme ventricular diastole. Ventricular systole is powerful, 

 and the ventricle becomes small and nearly colourless in systole, contrasting with its contractions 

 VOL. XXXVI. PART II. (NO. 16). 3 Q 



