422 



DR THOMAS R. ERASER ON STROPHANTHUS HISPIDTJS. 



Experiment CXXV. — Normal saline followed by solution of extract of Strophantus 

 in saline, 1 : 50,000 (Plate XIX.). 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



1 



24 * 





39 



32 " 





79 



321 





2 



25 





40 



32 





80 



32 





3 



27 





41 



33-8 





81 



30 





4 



27 



co 



42 



33-8 





82 



29 





5 



27 



r£ 



43 



33 





83 



29 





6 



26 



c3 



44 



33 





84 



29 





7 



26 





45 



33 





85 



29 





8 



26 





46 



33 





86 



29 





9 



27 





47 



32 





87 



29 





Strophanthus solution 



48 



30 





88 



28 





turned on. 



49 



30 





89 



28 





10 



30^ 





50 



30 





90 



27 





11 



32 





51 



30 





91 



27 





12 



32 





52 



30 





92 



25 





13 



32 





53 



29 





93 



25 





14 



29 





54 



30 





94 



23 



GO 



3 



15 



30 





55 



28 



rg 



95 



22 





16 



28 





56 



28 







96 



17 



Pi 

 03 



17 



28 





57 



28 





97 



17 



a. 



18 

 19 



27 

 28 





58 

 59 



27 

 27 



o 



98 

 99 



17 

 12 



o 

 r! 



20 



27 



QQ 



a 



60 



27 



B4H 



o 



100 



7 



O 



21 



28 



61 



27 



4J 



O 



101 



8 



+3 

 o 



22 



28 



c3 



62 



27 



OS 



102 



5 



o9 



u 



4^ 



23 



28 



a* 

 o 



63 



27 



H 



w 



103 



7 





24 



28 





64 



27 





104 



7 





25 



28 



'4-1 



65 



27 





105 



10 





26 



31 



O 

 43 



66 



27 





106 



9 





27 



30 





67 



25 





107 



12 





28 



30 



49 



68 



27 





108 



13 





29 



30 



H 



69 



27 





109 



13 





30 



30 





70 



25 





110 



13 





31 



30 





71 



27 





111 



15 





32 



30 





72 



27 





112 



15 





33 



32 





73 



27 





113 



16 





34 



32 





74 



30 





114 



16 





35 



32 





75 



33 





115 



16 





36 



32 





76 



33 





116 



16 





37 



34 





77 



33 





117 



16 





38 



34 





78 



34 





118 



16 





The experiment was continued for an hour longer, when the flow was 15 minims per 60 

 sec. Considerable oedema occurred, as the frog weighed 277 grains before the experiment, 

 and 392 grains at its termination, representing a gain in weight of 115 grains. 



The effects of this dilute solution of extract are seen to be dilatation of blood-vessels 

 followed by very slowly increasing contraction. If the curve of this experiment be com- 

 pared with that of Experiment CXLIV. (Plate XX.), in which digitalin, also in a solution 

 of 1 : 50,000 was used, a very marked difference will become apparent. In solutions of 

 equal strength, extract of Strophanthus produced no contraction in 80 min., whereas 

 digitalin practically occluded the blood-vessels in 17 min. 



