428 



DR THOMAS R. FRASER ON STROPHANTHUS HISPIDUS. 



solution of extract of Strophanthus had been allowed to flow for some time through the 

 blood-vessels, a weaker solution of digitalin was substituted in the same frog for the 

 solution of Strophanthus. 



Experiment CXXXIV. — Normal saline followed by solution of extract of Stroph- 

 anthus in saline, 1:2000, and 15 min. afterwards by solution of digitalin in saline, 

 1 : 20,000 (Plate XIX.). 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



1 



271 





16 



25 ^ 





31 



3 ] 





2 



26 





17 



26 





32 



3 





3 



25 





18 



24 



09 



33 



2 





4 



28 



i P 



19 



24 



o ^3 



34 



1 





5 

 6 



30 



28 



Is 



Xtl 



20 



21 



22 

 22 



"5 & 



35 

 36 



1 



1 





7 



27 





22 



22 



H is 



37 



1-5 



p 



8 



27 J 





23 



22 



XII 



38 



1-5 



'cS 



Strophan 



thus solution 



24 



20, 





39 



0-8 



WO 



turn 



ed on. 



Digitalin solution 



40 



0-8 



P 



9 



28] 





turned on. 



41 



0-5 





10 



27 



to 



25 



2(T 





42 



0-5 





11 



27 



-P 



26 



12 



c 



43 



0-8 





12 

 13 



26 



28 



> c3 c$ 



27 

 28 



8 

 6 





44 

 45 



0-8 



0-8 





14 



26 



W 2 



29 



3 



fi 



46 



0-8 J 





15 



25 J 



w. 



30 



sj 









At 46 min., the flow of the digitalin solution was stopped, and the original Stroph- 

 anthus solution again turned on ; but no effect was thereby produced, the blood-vessels 

 continuing to remain in the nearly occluded condition caused by digitalin. No oedema 

 occurred in this experiment, as the weight of the frog both before and after the experi- 

 ment was 355 grains. 



Experiment CXXXV. — Normal saline followed by solution of extract of Strophanthus 

 in saline, 1 : 500, and 45 min. afterwards by solution of digitalin in saline, 1 : 20,000 

 (Plate XIX.). 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Time in 



Flow per Min. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



Minutes. 



in Minims. 



1 



60] 





11 



70] 





23 



75] 





2 



60 





12 



65 



CO 



24 



72 



oi 



3 



65 





13 



65 



A 



25 



64 



rfi 



4 



69 





14 



67 







s 



26 



65 



c 



a 



5 



70 



S 



15 



72 



Oh 



27 



67 



On 



6 



70 



03 



16 



73 



o 



28 



67 



o 



7 



72 



w. 



17 



75 





29 



61 





8 



71 





18 



80 



o 



30 



60 



o 



9 



72 





19 



76 





31 



56 





10 



72 





20 



79 



oj 



En 



32 



52 



E 



Strophanthus solution 



21 



78 





33 



49 





turned on. 



22 



75 J 





34 



50 J 





