136 



DR THOMAS R. FRASER ON STROPHANTHUS HISPIDUS. 



Experiment CXLIII. — Normal saline followed by solution of digitalin in saline, 

 I : 100,000 (Plate XX.). 



Time in 



Flow per Min. in 



Time in 



Flow per Min. in 



Time in 



Flow per Min. in 



Minutes. 



Cub. Cent. 



Minutes. 



Cub. Cent. 



Minutes. 



Cub. Cent. 



1 



i-r 





28 



1-2' 





57 



0-4 





2 



1-9 





29 



1-3 





58 



0-4 





3 



19 





30 



1-2 





59 



0-4 





4 



1-9 





31 



1-2 





60 



0-4 





5 



1-9 





32 



1-2 





61 



0-3 





6 



2-0 



33 



1-2 





62 



0-4 





7 



2-0 



OQ 



34 



11 





63 



0-4 





8 



1-9 





35 



11 





64 



0-4 





9 



2-0 





36 



1-1 





65 



0-3 





10 



2-0 j 





37 



1-1 





66 



0-3 





Digitalin solution 



38 



1-0 





67 



0-4 





turned on. 



39 



1-0 





68 



0-3 





11 



2'0~ 





40 



0-9 





69 



0-3 





12 



2-1 





41 



0-9 



Q 



70 



0-3 



a 



13 



2-1 





42 



0-9 



c3 



71 



0-3 



► .-a 



14 



1-9 





43 



0-8 



A 



72 



0-3 



bD 

 S 



15 



1-6 





44 



0-8 



73 



0-3 



16 



1-6 





45 



0-7 





74 



0-3 





17 



1-5 





46 



0-7 





75 



0-3 





18 



1-4 



g 



47 



07 





76 



0-2 





19 



1-4 



\% 



48 



0-6 





77 



0-2 





20 



1-4 



Ep 



49 



0-6 





78 



0-2 





21 



1-3 



s 



50 



0-6 





79 



0-2 





22 



1-3 





51 



0-5 





80 



0-3 





23 



1-3 





52 



0-5 





81 



0-2 





24 



1-3 





53 



05 





82 



0-3 





25 



1-3 





54 



05 





83 



0-2 





26 



1-3 





55 



0-4 





84 



0-2 





27 



1-2 J 





56 



0-4 





85 



0-2 





Moderate oedema was produced, the frog having gained 85 grains. The weight 

 before the experiment was 324 grains, and at its termination 409 grains. 



As contrasted with the experiment in which 1 : 100,000 solution of strophanthin 

 (CXXXVL), had been perfused without almost any effect on the blood-vessels, in this 

 experiment with 1 : 100,000 of digitalin, the vessels were contracted to one-half in 27 

 min., to one-quarter in 40 min., and to one-tenth in about 60 min. The curve of this 

 experiment (Plate XX.), may instructively be compared with that of the above referred to 

 experiment with strophanthin (Plate XX.). 



[Experiment CXL1V. 



