122 Germ of the Southern Cattle Plague. 
in the same species of animals under natural conditions, when healthy 
animals of the given species are inoculated with artificial cultivations 
of the germs in question. Our experiences here completely upset 
Hueppe’s hypothesis. 
The American Swine and Southern Cattle Plague should, accord 
ing to Hueppe, be identical diseases with those mentioned as con- 
sidered so by him in Germany, because, according to his condition, 
the germs are identical, Hueppe’s entire argument is completely 
nullified by the following facts :— 
First.— There is no Southern Cattle Plague known in Europe. 
Second.— Cattle and Swine run together in this country, and one or 
the other may have respectively Swine or Cattle Plague, and yet the 
other species will never become ill, even from the closest contact with 
members of the other species sick with its peculiar plague. Hens can 
feed on hogs dead from the swine plague, from the ground polluted 
with their discharges, even picking out grain from the same, and 
still remain wel¥; and the same is true of the hogs with regard to 
Hen Cholera and the Southern Cattle Plague. 
Hence, no matter how these germs may resemble each other, when 
artificially examined, they fail in the one great factor necessary to 
make the diseases produced by them identical; they do not have the 
same physiological chemical attribute with regard to a given something 
produced, which invariably decides the pathogenetic results produced by 
a given germ. Notwithstanding the latter fact, these diseases all have 
a very close relation to one another. They are all extra organismal, 
local land septicemia. Each one, however, has something peculiar 
about them that prevents them from being identical diseases, aside 
from any action of the germ. 
Each species of animal in which they occur has some unknown 
constitutional idiosynerasy which renders its members susceptible to the 
action of a given germ, and each of these germs has some peculiar 
unknown biological idiosynerasy by which alone it infects, naturally, 
but a given species of animal life. 
These two factors, together, can alone decide the identical ques- 
tion. What we can do artificially, by the inoculation of those ani- 
mals that the disease does not occur in naturally, has no necessary 
relation to the question whatever. 
There are, however, other phases in the development of these 
germs of a bio-morphological character. For instance, as already 
said, we may see two or three individuals of the mature type united 
Ph ee eee ee 
