ACTION OF CHLOROFORM UPON THE HEART AND ARTERIES. 337 
the proportion of ammonia be less and the animal be already completely under the influ- 
ence of an anesthetic, the ettect of the addition of the vapour of ammonia or ammoniated 
alcohol to the chloroform inhaled is strikingly beneficial. The blood-pressure falls but 
slightly even during a prolonged period of inhalation—the strength of the heart is well 
maintained—and the tendency to failure of respiration, which is so marked a feature 
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Fic. 22.—Tracings showing in a comparative manner in the same animal the difference of effect between inhalation (A) ot 
pure chloroform, (B) of a mixture of chloroform with ammoniated alcohol (9 to 1), and (C) of a mixture of chloroform and 
absolute alcohol (9 to 1). 
Note in A the rapid fall of blood-pressure and the speedy failure ot respiration ; in this case the heart continued to 
beat after the respirations had ceased. After a respiratory arrest of more than a minute, during which the heart showed 
strong tendency to inhibition, artificial respiration by chest compression was resorted to (the beginning of this is shown) : 
in rather more than a minute the blood-pressure rose—the natural respirations were then resumed. Note in B and C the 
very slow and slight fall of blood-pressure, and the complete maintenance of respiration during the whole time of adminis- 
tration. In all three cases the air of respiration was charged as strongly as possible, at the ordinary temperature of the 
laboratory, with the vapour to be inhaled. 
a, respirations ; 6, blood-pressure ; c, time in 10 secs. ; d, signal showing period of administration. In all cases there 
was distinct corneal reflex immediately prior to the administration, and this disappeared within 1 minute. 
