338 PROFESSOR E, A. SCHAFER AND DR H) J. SCHARLIEB ON THE 
of strong chloroform inhalation, is considerably diminished. The comparative effects 
of inhalation of chloroform alone and of chloroform plus ammoniated alcohol are shown 
in the tracings A and B reproduced in fig. 22, and the beneficial results of substituting 
a mixture of chloroform contaiing alcoholic ammonia for pure chloroform are illustrated 
in the tracing given in fig. 23.* 
(4) Alcohol Vapour.—lIn order to determine how much of the beneficial effect of 
the mixture of alcoholic ammonia with chloroform was due to the alcohol used as a 
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Fic. 23.—Beneficial effect upon blood-pressure, heart, and respiration of substituting ammoniated alcohol and chloroform (1 to 
9) for the pure chloroform which was being administered to a dog. 
a, blood-pressure ; 6, heart-beats, recorded by a needle passed through chest wall ; c, respiration ; d, time in 10 secs. 
Notice the increasing strength of the heart-beats and of the respiratory movements. 
It is also seen that the dropped heart-beats due to vagal inhibition which were occurring during chloroform alone 
gradually disappear as the result of adding ammoniated alcohol to the chloroform. 
vehicle for the ammonia, we next proceeded to investigate the results of using for 
inhalation the vapour given off from mixtures of chloroform and alcohol. We were 
somewhat surprised to find that the results were nearly as beneficial when alcohol alone 
was used, as when alcoholic ammonia vapour was employed. The difference between 
the effect produced upon blood-pressure and respiration by inhalation of pure chloroform 
in the one case, and by inhalation of a mixture of chloroform containing 1 part in 10 
* The addition of ammonia gas to the chloroform to be used for inhalation was advocated by J. DUNCAN 
Menzizs (Brit. Med. Jour., vol. i1., 1895, p. 871). 
