130 Di; ALEXANDER BRUCE 



results of the experiment of section of the nerve, and further researches are obviously 

 needed. 



So far as could be ascertained from a mere anatomical examination, no clue as to 

 differentiation of function of the various groups can be obtained from the form of their 

 cells. There were no groups of cells distinguished by a special size or form of 

 cell. There was, it is true, a tendency for the cells in the lower dorsal 

 region to be larger than in the cervical and upper dorsal regions, but these large cells 

 were intermingled with small ones, and nowhere was there any appearance of a group 

 so distinctive as to suggest that its function was essentially different from a 

 neighbouring group. 



It is of interest to note that although the total number of cells on the two sides 

 was, as far as could be ascertained, fairly nearly equal, yet that in the cervical and 

 upper dorsal region there was a preponderance in favour of the left side. In the tenth 

 dorsal region, on the other hand, there was a very remarkable preponderance in favour 

 of the right side. 



As yet little has been done to connect the pathological changes with disease. The 

 intermedio- lateral tract appears to escape entirely in cases where there is a chronic 

 degeneration of the anterior cornual cells in progressive muscular atrophy and in amyo- 

 trophic lateral sclerosis. This may be due to a difference of power of resistance or to a 

 difference of vascular supply. In one case it has been found to be degenerated in 

 connection with erythromelalgia. It may be hoped that future research will succeed in 

 explaining symptoms of visceral and vascular diseases hitherto imperfectly understood. 



LITERATURE. 

 Anatomy. 



J. Lockhart Clarke, Phil. Trans., 1851, vol. ii. p. 613, and 1859, p. 445. 



W ai.deyer, Ahth. der Ki'mig. Akad. der Wissenschaft, Berlin, 1888. 



Edingeb, tJber den Bau der nervosen Centralorgane, 1889 and 1904. 



Obebsteiner, Der Ban der nervosen Centralorgane, 1896, p. 226. 



Lenhossek, Der Bau de.v Nervensystems, 1895, p. 343. 



Van (Ikiigchten, Anntomie du Systeme Nermux, vol. i. p. 352. 



Toldt, Lehrbueh der Gewehlehre, 1888, p. 173. 



Debibbbb, La Moelle Epiniirr et I'JSnciphale, 1894, p. 60. 



Schmaus-Sackl, Pathologisches Anatomie des Riickenmarks, p. 6. 



Schwalbe, Lehrbuch der Neurologie, 1881, p. 337. 



Sherrington, "Out-lying Cells in the Mammalian Spinal Cord," Phil. Trans. Boy. Soc, London, 1890. 



"The Lumbo-Sacral Plexus," Journ. Physiol., 1892, p. 694. 

 Mutt, "The Bi-polar Cells of the Spinal Cord and their Connections," Brain, 1890, p. 433. 

 Argutinsky, "On a Regular Segmentation in the Grey .Matter of the Spinal Cord in the New-Born, and on 



the Middle Cells/' Areh.f. mikros. Anat., vol. xlviii., 1897, p. 504. 

 Ontjf and Collins, Sympathetic Nervous System, 1900. 

 Ford Robertson, Pathology of Mental Diseases, L900. 



