598 DR MARSHALL AND MR W. A. JOLLY 



since the transplanted ovaries, while still maintaining their functions (at least in many 

 cases), had lost their normal nervous connections. It is extremely probable, therefore, 

 that the uterus is dependent for its proper nutrition upon substances secreted by the 

 ovaries, not merely at the heat periods and during pregnancy, when they show their 

 greatest activity, but throughout the whole of the oestrous cycle. 



The expenses of the investigation were defrayed by grants from the Government 

 Grant Committee and from the Carnegie Trust. 



POSTSCRIPT. 



Since this paper was communicated, Carmichael has published a paper on " The 

 Possibilities of Ovarian Grafting in the Human Subject." He describes numerous 

 experiments on homoplastic transplantation in rabbits, the majority of which were 

 successful in parts. Carmichael is of opinion that in larger animals, and in the human 

 subject, the ovary when transplanted is unlikely to retain its complete functional 

 activities owing to partial degeneration, although it is probable that portions of the 

 graft may be got to survive. 



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