POISONED ARROWS OF THE ABORS AND MISHMIS OF NORTH-EAST INDIA. 917 



Table XVII. — Poison of Abor Arrows from the Government of India. 

 Frogs. — Injection under the skin of a leg beloio the knee. 



Date. 



1914. 

 Jan. 7 



Oct. 12 



Weight 



of 

 Animal. 



33 



„ 12 17-5 



12 



17 



Dose 



per 



Kilo. 



0-005 



0-025 



005 



0-1 



Actual 

 Dose. 



0-000165 



0-00045 



Result. 



0000875 



Recovery 1 



Killed " with 

 chloroform 

 on 19 th clay. 



Death in 6 to 

 7 days. 



Death in 

 3 days. 



to 



0-0017 



Death in less 

 than 2 days. 



Notes. 



No symptom observed except indisposition to go 

 about. After death, no abnormal appearances 

 under skin, no blood in alimentary canal. 



On 3rd day, discoloration and slight swelling 

 of thigh and leg of injected limb. On 4 th day 

 motor weakness. No blood passed. After 

 death, blood in water of dish ; thigh, leg, and 

 foot muscles of injected limb very red, those 

 of leg being intensely so ; no haemorrhages in 

 opposite limb or elsewhere, except slight 

 haemorrhages in pectoral region and flank of 

 side injected. In stomach and small in- 

 testines a little blood, and in large intestine 

 a considerable quantity. 



On 2nd day, a little blood at nose and mouth ; 

 thigh and leg of injected limb discoloured, 

 and foot swollen. After death, whole of 

 injected limb very d;irk, almost black ; blood 

 in fluid in dish ; a little blood at urostyle 

 and punctated haemorrhages in muscles of 

 injected thigh, leg, and foot, mostly in leg ; 

 no haemorrhage in opposite limb or elsewhere. 

 In stomach and large intestine a considerable 

 quantity of blood, and a little in upper part 

 of small intestines. 



After death, punctated haemorrhages of leg and 

 foot of injected limb ; none of its thigh or of 

 any part of opposite posterior extremity, but 

 much hemorrhagic discoloration of tissues 

 under skin at anterior aspect of abdomen 

 and thorax. Much blood in stomach, and a 

 little in small and large intestines. 



The experiments demonstrate that, even when the locality of injection is distant 

 from the abdomen, haemorrhages into the alimentary canal are produced. 



Although no attempt was made to define the minimum lethal dose in these two 

 series of experiments, the records in Tables XVI and XVII show that, even when 

 injected in distal localities, so small a dose as from 0'005 to 0"025 grm. per kilo is 

 sufficient to produce death. 



In the experiments in which the injection was made below the knee (Table XVII), 

 the experiment with 0"1 grm. per kilo is noteworthy as it shows that while much 

 haemorrhage and congestion were produced in the injected leg, the thigh of the same 

 extremity above the knee presented only normal or nearly normal appearances, 

 although much blood had been extravasated into the anatomically distant alimentary 

 canal. 



